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HOW CREATINE AFFECTS THE BRAIN...

January 25, 2026 / 01:43

This episode discusses the effects of creatine on muscle and brain health, featuring insights on supplementation and cognitive benefits.

The host shares personal experiences with creatine, noting its traditional association with bodybuilding. They highlight recent findings on creatine's impact on brain function, particularly during stress.

Specific studies are mentioned, including how creatine can counteract cognitive deficits caused by sleep deprivation. The host emphasizes that higher doses can lead to improved cognitive performance.

Overall, the episode promotes creatine not just for physical fitness but also for mental clarity and energy levels throughout the day.

TLDR

Creatine enhances muscle strength and brain function, especially under stress and sleep deprivation.

Episode

1:43
00:00:00
Creatine has been around for I mean ever. In my mind, it was like one of those gym bro things. I don't need to be
00:00:06
swole. And then over the last five years or so, the effects of creatine on the brain
00:00:14
started to really get my interest. It can increase muscle mass. It can increase muscle strength in combination
00:00:20
with resistance training because you're able to regenerate and make energy faster. What are the effects on the
00:00:27
brain? It turns out if you can give your brain more of that creatine, particularly under a period of anything
00:00:35
that's causing stress, that's where creatine shines in the brain. Five grams
00:00:39
a day, your muscles are greedily consuming it, particularly if you're working out. Anything above that kind of
00:00:45
spills over to the brain. 10 grams of creatine, increased creatine levels in several different regions of the brain.
00:00:51
If you supplement with 10 grams of creatine or even go higher than that, like 20 grams of creatine, and it's been
00:00:57
found that if you take someone and you sleep deprive them for 21 hours, and give them about 25 to 30 grams of
00:01:07
creatine, it completely negates the cognitive deficits of sleep deprivation. Actually, not only does it negate the
00:01:15
cognitive deficits of sleep deprivation, it makes people function better than if
00:01:22
they were well rested. That's where I was like, wait a minute. Well, I will say even at the 10 grams, for me, I
00:01:30
don't feel that mid-after afternoon crash when I have the creatine. So, I've
00:01:34
been a big fan of the creatine. Um, not only for the muscle, especially because,
00:01:38
you know, working out is something that's very important, but for the brain as well.

Episode Highlights

  • Creatine's Surprising Brain Benefits
    Creatine isn't just for muscles; it significantly boosts brain function, especially under stress.
    “Creatine shines in the brain during stress.”
    @ 00m 35s
    January 25, 2026
  • Negating Sleep Deprivation Effects
    Supplementing with creatine can counteract cognitive deficits caused by lack of sleep.
    “It completely negates the cognitive deficits of sleep deprivation.”
    @ 01m 07s
    January 25, 2026

Episode Quotes

  • Creatine shines in the brain during stress.
    HOW CREATINE AFFECTS THE BRAIN...
  • It completely negates the cognitive deficits of sleep deprivation.
    HOW CREATINE AFFECTS THE BRAIN...
  • I don’t feel that mid-afternoon crash when I have the creatine.
    HOW CREATINE AFFECTS THE BRAIN...

Key Moments

  • Brain Boost00:12
  • Sleep Deprivation Study01:00
  • Personal Testimony01:30