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How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation

October 24, 2025 / 27:20

This episode of Marketing Matters covers topics including artificial intelligence in marketing, data science, and the role of technology in pharmaceuticals. Guests Barbara Khan and Americus Reed discuss these themes with Shawn Buick, the Senior Vice President of AI and Data at Amgen.

Shawn Buick shares his background, detailing his journey from Stanford to major companies like Google, Facebook, and Nike. He emphasizes the importance of technology in understanding marketing and how it intersects with data science.

Buick explains his current role at Amgen, focusing on using AI and data to improve medicine development. He discusses the complexities of the pharmaceutical industry and how AI can enhance efficiency in scientific research.

The conversation also touches on the challenges of adopting AI in large organizations, referencing a controversial MIT paper that claims most AI pilots fail to generate value. Buick argues that success depends on aligning technology with business strategy and organizational culture.

Finally, Buick provides examples of how AI can streamline processes in biotechnology, highlighting the potential for AI to create new roles and enhance human capabilities rather than replace them.

TLDR

Shawn Buick discusses AI's impact on marketing and pharmaceuticals, emphasizing efficiency and the importance of organizational culture in technology adoption.

Episode

27:20
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Hello and welcome. You're listening to Marketing Matters on the Wharton Podcast
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Network, our weekly podcast where we analyze the latest in advertising, marketing, customer behavior, new
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product launches, retailing, and pharmaceuticals. Uh, I'm Barbara Khan, the Patty and JH Baker Professor of
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Marketing, and I'm joined by my co-host, Americus Reed, the Whitney M. Young Jr.
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Professor of Marketing and the brand identity theorist. Hello, Americus. >> Hi, Barbara. So, uh, this is the first
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week of classes. It's an incredible sort of energy on the campus. I'm loving it.
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Uh, one of the things we talked about today is level setting. >> I just mentioned it's your first week of
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classes. I've been teaching seven weeks. >> Seven weeks in. So, you're like, listen,
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I may be I'm into it now. America, you're brighteyed and bushy tail, but
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hey, it's going to catch up with you. >> We're all on midterms. I don't know
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where you are. >> I'm introducing the syllabus. And so, yeah. No, it's it's it's fascinating
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that you mentioned that because you know all of the things that are going on campus. One of the things I talked about
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today, Barbara, is we're talking about marketing and people think marketing is
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just advertising, but I was trying to explain to my class marketing is about strategy. And in fact, marketing
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actually starts with science and ends with art. And so I'm very fascinated by
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this interface of data science, artificial intelligence as a new technology that is making its way into
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marketing strategy, various ways that it's happening and all of these different interfaces. And so have you
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got anything for me today that can help illuminate this and further allow me to make the case to my students that
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there's a lot going on under the hood with respect to marketing strategy? Oh,
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well actually we have a very interesting guest today who can talk about a lot of
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those things because he's have a long and varied career. I'd like to introduce
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Shawn Buick who's currently the senior vice president of artificial intelligence and data at Amgen which is
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a pharmaceutical or biotech or anyway health kind of related company but he has a long history starting out at
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Stanford as a psychology and biological science major all the way through Google
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and Facebook and Nike. So he's kind of been at the right place at the right time. Anyway, welcome Sean to our show.
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>> Thank you, Americas. Thank you, Barbara. It's so great to be here. >> So, let's build on on Americas's um
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quest or introduction in some sense or question and just quickly go through your background because you do have a
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knack of being in the right place at the right time starting well Stanford wasn't
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the right place. You should have been a Wharton, but okay. >> Had to get that plug in. Very, very well
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done, Barbara. But then uh I think you went first to Google then to Facebook then to Nike and now to Amgen just as
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each one of those areas was doing some pretty interesting area connecting marketing with data science and now what
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I really like to talk about is what you're doing at Amgen. But let's start
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with your history. >> Sure. Yeah. I got my start uh up at Stanford and um I was working in a
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neuroiming lab. So this was right around the time you know this these new brain scanners were be being able to gaze into
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the working human mind functional magnetic resonance imaging. Um and and there were kind of two things that
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happened there. I think the first was you know this new technology allowed us to for the first time answer some
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questions that for 70 years in cognitive science weren't really answerable. And
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so I became really convinced up until that point I'd been you know studying the science but I became convinced that
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technology was going to be really important in understanding the world. And then the second thing was I had to
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learn how to code because this these data sets were so much bigger than the reaction time and wet lab and um you
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know survey data that sort of everybody was using at the time. And so that's
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what really got me started um in in my career and I I got a job at Google right at the beginnings of what you would now
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call consumer data science. >> Um had had just a a you know wonderful set of mentors there as we were um sort
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of exploring what was possible with this field. I went to Facebook and helped them launch the the ads business um
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where I led the the measurement science team, the data science team on the on the ads business. And then I spent the
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last 10 years at Nike where um I helped them with their direct to consumer digital transformation leading their
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data science and analytics and customer insights teams there. But as you said, I
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made a big uh switch about a year ago. So now I met I'm at Amgen which um if if
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folks don't know is one of the world's leading biotechnology companies. It
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makes medicines um for things like uh cancer and inflammatory disease and cardiovascular disease and rare disease.
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Um it's been around for for over 40 years. It was sort of one of the pioneering companies in the biotech
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revolution of the 1980s. Um, and my job here is to try to figure out how we can use AI and data uh to make better
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medicines for for patients. >> So, let me just build a little on this. Now, you've been there a year and um I
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mean I know you were what that health what did you say bio health or biological science undergrad major but
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that's not like major health credentials. So, but obviously they saw some advantage in what you did do for
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the last 10, 20 years. Uh, but how have you like learned about what Amgen does and h how did how did you get up to
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speed? How did you do that? >> Yeah. And and it's been a long time since I took my last biology class at at
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Stan Smith. >> Yeah. And I mean, the science here is is really complex. you know, it's genetics,
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it's it's biology, it's pharmarmacology. Um, and so it has been definitely a a a
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big ramp to to learn all about what we do at Amgen. And and you know, it is pretty different than online ads or
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shoes in a few in a few ways. I mean, I think the first is just the fact we're,
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you know, making medicines for for patients, which creates this incredibly high standard around reliability and
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safety and compliance and scientific accuracy. Um, but it is a scientific discovery, especially in in this space.
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Um, you know, where you're trying to take this molecule and turn it into a a
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medicine. It it uses really large data sets. It's actually surprisingly quantitative for me. I mean, there's
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definitely beers and labs and experiments, but it's also very quantitative. Um, and and it's
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increasingly relying on technology because the data sets are huge and these, you know, new artificial
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intelligence and machine learning algorithms we think um has has the potential to really change um sort of
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how we bring these these medicines to patients. So, so some of it is definitely new and and hard and and a
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ramp, but some of it feels, you know, much more comfortable, the the core first principles of data science or or
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the um, you know, underlying technology stack and the partners and things like that.
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>> So, if everybody is using AI, then is how do you differentiate? I mean, it
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seems like if you have AI, everybody's doing the same thing. Then how how does
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that work? No, you you bring up a great point, Barbara, and and I do think there's a lot of convergence now on how
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well these algorithms perform, you know, so in the old days, um you know, when I
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was getting my start as a as a data scientist, you know, your your magic sauce was very much like how good your
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your algorithm was, how good your model was. Um nowadays I think I think companies should be thinking about two
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things and and certainly we are here at at Amgen but I think if you look across uh you know my work work previously
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there was it was the same concepts you know the first is you the underlying data that you have as a company is is a
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pretty interesting differentiator and and I'm super excited about some of the
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data we have here at Amjen you know genetics data a long history of designing proteins um and molecules and
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and all those scientific experiments along the way that there's that you know
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that that set of data uh is is a really interesting differentiator >> and then I think increasingly what
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you're seeing is that there is an art and a science because you mentioned kind
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of the art and the science um of how do you implement these algorithms in a way that you know is impactful in a way that
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gets to scale quickly >> um and and realizes whatever impact you're trying to drive at at your
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company. And I think in both spots, there's going to be differences in how successful companies are. And so, um, I
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think I think that's kind of one of the most important and underappreciated parts of of how to win here.
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>> I love that point, Sean. One of the things that I talked to my class Sean is
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the idea of adoption of AI technologies and the statement that you made which is
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how do you make the company strategy infused deeply with the DNA of AI that seems not necessarily easy because you
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have different folks maybe even if it's a large company and you know aside from
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just having a bunch of young people who are sort of born into it in your company
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how do you go about creating that the right organizational culture and atmosphere
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where the adoption of these technologies and understanding of how to use and deploy them appropriately and well
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differentiated like Barbara said, how do you make that happen? What are the what
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are the things that you do to create the cohesiveness inside the building to be able to adopt that kind of culture?
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>> Yeah. I mean, this is a podcast, right? So, we have to have some controversy.
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Can I bring up the MIT AI paper because it Yes. Definitely a controversial topic
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and I think one that's worth digging into a little bit because I think it it
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strikes right at the heart of of kind of your question. Okay. So for if >> if people are not tracking, there was a
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a paper by MIT that came out uh probably four weeks ago that you know the headlines have all said 95% of AI pilots
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in companies don't generate value. Um now that's the headline. The real story
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I think is is is twofold. So the first story is that if you're in a big company
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and you do a pilot, it never generates scale business value. That's the whole
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point of a pilot, right? Is it's little. Um now there's a muscle around how do
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you choose the right pilots? because pilots are only valuable if they teach you something you didn't know or derisk
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an investment by by you know trying it out in a specific zone or or sometimes I think what you as you mentioned you know
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shines a light on a success story that can absolutely inspire and teach your your colleagues and your workforce a
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path forward but lots of pilots lots of sort of poorly thought through poorly targeted random pilots is not a measure
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of success. And there's a lot of companies, I think, doing way too many pilots that are kind of not ever going
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to generate real value because then you have to have the practice and the and the skill set and the technology stack
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and the monitoring capabilities to take the winners and get them scaled and adopted and and that I think is a is is
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a real lesson um from this paper. Now, now why did these 95% of these programs in this paper fail?
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This isn't always in the headline. It wasn't the AI technology. It wasn't like
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the algorithms were crappy. It wasn't that the that the AI failed. It was everything else about it. There wasn't
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alignment on the budget. Business processes weren't evolved. There wasn't
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receptivity on the part of the people using it. They didn't get adoption. And
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and so that speaks exactly to your point, which is even if you have an amazing capability, if if you don't get
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everybody else lined up around it in a big company, you're never going to get
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the the business value out of it. And I think that's another piece that companies are struggling with is is how
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do you line up everything such that you can really pull these through to value um and and make an impact on the on on
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whatever mission you're trying to accomplish. >> Well, so how do you do it?
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No, it I I think it's this there's there's three pieces. I think you have
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to have the discipline around where are you going to do the pilots and what are they designed to teach you? And you
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know, here at Amgen, we have a we have a very rigorous process. It it's not anybody can run any pilot anywhere
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around AI. We're we're directing those pilots at specific zones that are going
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to teach us something. You have to have this muscle around how do you take a great pilot and and get it
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to scale. So and and and you know that's a technical question around you know do
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you have the right data infrastructure do you have the right um technology portfolio do the right monitoring uh
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programs to get these algorithms implemented and then there's all of the change management stuff that you know is
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not all that different than every other technology transformation that you guys have studied you know that we've looked
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at digital marketing you know 15 years ago direct to consumer you know 10 years ago So um but if but if you don't have
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all three of those I think it's really hard to make a big impact and and you
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know one or two of them isn't enough. >> So let me let me just summarize that. So
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like the first one is kind of how to ask the right questions right where to focus
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is the first thing and then and you can ask a lot of wrong questions but understanding where you're focusing is
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basically what you're saying and I could totally see how that'll differ from firm
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to firm to firm. So it wouldn't result in the same thing. And then once you get
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viable ideas, implementing and and bringing to and operationalizing and then scaling is a whole other issue. And
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then the third one is getting the organization around this new is that it >> Yeah, I think that's a great a great
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summary. It's it's you know the discipline around pilots, where you play, how you test ideas, how you turn
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the Yeah. turn turn the big ones the the best into impactful scale programs and then how do you line up all of the
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pieces that are necessary to to make to make the impact through those through those uh scale pilots for sure. So it
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seems like how to do it right would suggest that there's like some measurement system or some objectives
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you and some like metrics that you have along the way in order to see if you're
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making prog is that kind of the way it goes or how do you know you're on the
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right track? Yeah, I look I think there are um you know a whole host of technical things we do to make sure
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these models are performing well and you know having thoughtful evaluation frameworks and um you know looking at
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their performance and um all of that stuff is is sort of the job of the data science team or the AI team. But I think
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you know the the bigger question goes back to that conversation we were just having around is it actually making an
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impact on your strategy. You know is it is it driving whatever outcomes you as a
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business are trying to are you trying to trying to enact. And that I think is the
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place where sometimes you know the plot gets a little bit lost. you focus too much on the technical implementations or
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the technology roadmap or the or you know the path that the that all the um the data and the algorithms and the
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technology stack need to be um all right and and sometimes you lose track of the
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the organizational and business partnership. I mean we understand what you're saying Sean which is like the the
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specific role of the technology needs to be managed in a way that is built around
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the synchronization of its adoption within the organization and how to in your case how to figure out the bi the
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specific biology that produces new opportunities for wellness products or health related uh protocols and things
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of that nature. So we definitely understand that it's just challenging because and whenever I hear a talk Sean
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on AI and you're a guru of this I sit back and I have to like suspend a lot of
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my judgment because I just don't know what you're talking about in terms of
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the technical pieces of it. You know all of these s sort of things. I understand
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the logic of it but I want to know much more to Barbara's point about you know
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how does this work? What is a what's an example of a specific pilot? if you could share that, you know, things that
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we've that you guys have done. Maybe that's the secret sauce and you can't
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talk about it, but like taking us through like here's something we did that's, you know, more public
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information now and here's an example of how we really brought in AI to really
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help us drive a specific understanding of a biological element that then turned into something that we could quickly
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scale and create something that adds value to the marketplace. Is there an example you could share with us?
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>> Sure. Yeah. I mean I think what is exciting and you know part of why I wanted to come to Amgen is I really do
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think biotechnology is is a spot where um some of the biggest advances in AI and data science are going to happen
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over the course of the next few years. I mean I I am so excited about what's
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possible and there's been some big breakthroughs and you know just last October
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um the winner of the Nobel Prize in chemistry was shared between the Google deep mic guys Dennis and a professor at
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the University of Washington David Baker. And you know what that that breakthrough um was was an algorithm
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called alphafold which was solving this like incredibly complicated uh problem in science which is how do
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you predict the way po proteins fold if you know the >> the the two-dimensional sort of
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structure of the protein can you predict the three-dimension structure and that >> interesting
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>> you know fortunately that actually happened after I joined Amgen because it
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attracted a whole bunch of news to the fact that AI and data science had had a potential potentially, you know, a big
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impact on on this field. But since I had joined a few months earlier, it looked like I was super smart and my timing was
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perfect as opposed to uh joining joining after the the news coverage. But that's
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an example, I think, of a big breakthrough. And, you know, there are relatively few of those along the way. M
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>> um you know I think the the more common instantiation of like an incredible
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impact of a of a data science uh project is actually just much more simple. So let me give you one.
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>> Okay. >> I did not know any of this a year and a half ago but but it turns out to be a
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good medicine the the molecules have to be a certain very narrow range of viscosity. M
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>> so like imagine >> you have a molecule it works pretty well but it's like peanut butter like too
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thick >> you can't inject that into the human body it's not going to work and so one
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of the most important criteria our scientists have to consider when they're designing these molecules is like how
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viscous is the solution of these of these proteins after after we uh engineer them and you know even that
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developing a a machine learning algorithm >> takes into account all the historical
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experiments >> got it >> and makes a prediction as to whether these molecules are going to be in the
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right zone to be a medicine >> can dramatically improve the efficiency of our scientists. So you know they
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don't have to make a hundred of these molecules and then see how viscous they
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are. they can use this algorithm and it dramatically cuts may not it may not be right all the time but it at least
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improves the efficiency of those scientists lets them direct their energy their creativity their time against a
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higher um fidelity of candidate right a small smaller pool more likely to be successful so you know those are the
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type of like blocking and tackling yeah incremental work >> that you know before we had access to
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all of that data being digitized and before our algorithms were powerful enough to make strong predictions, you
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couldn't couldn't reduce that workload. You couldn't shape shape where they're
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spending their time and attention. >> Interesting. >> That's the type of stuff just across the
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board we're looking at of how do you you know add a little bit of data science
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into the day of a protein engineer or a biologist or a geneticist um or a process engineer um you know a supply
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chain expert, right? And and and just incrementally move the needle on how efficient and effective they can be. So
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Sean, one of the things I'm interested in as you're telling us the critical
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role that AI does play and how it can really make things better. One of the things people are really afraid of is AI
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replacing other, you know, people working at a company. But the way you're describing it, it doesn't sound like
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that to me, and I wonder if you agree with it. It actually sounds like there's
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more room for people who know how to use AI and are trained to use AI and it might even provide more jobs than less.
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I almost got that impression from what you're saying, but I don't know if you
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want to go so far as to say something like that. >> Yeah, I'm no economist, so I won't weigh
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in on on maybe the um the economics of it, but I'm I'm thinking about it in in
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two ways. I think as we're implementing AI systems today, that human AI interface is actually critically
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important. And so, you know, we call it human in the loop. that's kind of the
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the term folks folks are using, but particularly when it pertains to like scientific inquiry and ensuring quality
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and compliance and adhering to like, you know, the incredibly high standards of of scientific accuracy that we have to
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adhere to. Having a human inside that system engaging with the technology and the AI algorithms themselves and the
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output is is critically important. And I I don't see that changing anytime soon.
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>> The other thing is as we as we build these systems, >> there's a whole set of new roles that
00:22:37
are being created >> that exist on on this edge. I mean, look, just just to zoom in on my career,
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I have never had a job >> in which there had been a prior incumbent in that job over the last 25
00:22:52
years. about you, but >> yeah, >> I don't want to overextend from an N of
00:22:57
one, Barbara, but I I think everyone would agree that's dangerous in in science and marketing.
00:23:04
>> But I do think it speaks to this is an exciting time. I mean when I look at my
00:23:11
whole career and and know I've been around data science since the really early days this is the single most
00:23:18
interesting exciting moment that I've seen in that time. I think the capabilities you know the combination of
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computing power and data that's that's been digitized and available um and the
00:23:33
performance of these of these new models is is really transformational. I think,
00:23:38
you know, tools like chat GPT are are just incredible. I'm sure many of your
00:23:42
listeners are are big users of it. >> Yeah, I'm sure they use it all the time.
00:23:47
>> And then, you know, I really do think one of the biggest challenges in data
00:23:50
science over the last 20 25 years has been just it's been really restricted to
00:23:55
people who are really highskilled like you know they know we know Python, know how to use the technology, work at a
00:24:02
company that has big data sets. But the other thing that's really fun here is is
00:24:06
this has really democratized the power of data and algorithms in a way that almost everybody out there listening can
00:24:12
probably find, you know, a handful of spots even just in their own lives, whether it's making shopping lists or
00:24:18
planning vacations or automating workflows, you know, getting work done faster. That's going to have a pretty
00:24:23
big impact. So, I'm I'm really excited about, you know, the positive impacts
00:24:27
that that these new technologies are going to have on on us at work and us outside of work. Yeah, Sean, this is uh
00:24:33
super intriguing to me. I I want to, you know, ask this question because I think
00:24:37
it's important when we have the gurus available to us to put them into the time machine and give us some insight
00:24:43
into their crystal ball about what is the state of the world in your domain, artificial intelligence, uh data
00:24:50
science, all of these things. Um what is that going to look like in your view five to 10 years from now?
00:24:57
Well, I am too good of a data scientist to get busted by making predictions too far into the future. So, I'm gonna I'm
00:25:04
gonna tell you what I think now and then maybe gaze just a little bit more approximately into the future. But um
00:25:09
you know, look, I think the biggest mistake people make in a moment like this around a big technological uh
00:25:17
revolution, evolution of of data science and algorithms and data is that they over focus on the here and now. the
00:25:25
failures of of technologies, the hype cycles that turn out to be, you know, overheated and they underestimate in the
00:25:34
medium term how pervasive and impactful some of these technologies can be. And I
00:25:39
I think that's the big disconnect I see right now between kind of the here and
00:25:44
now. you know, we've all had a moment where the algorithm didn't do what we
00:25:47
wanted it to do or there's not enough data to make the prediction or, you know, chatbt gives you a lousy answer.
00:25:53
And and those things are true. Um, but I I do think in the medium term, folks are
00:25:59
underestimating how big of an impact uh this this new set of capabilities is going to have. And that's a big part of
00:26:07
why I came to Amjen is I'm I'm really bullish on what I think is is possible
00:26:11
here. Now, you got to do all the stuff we talked about to to actually make the impact at at scale. Um, but I I think uh
00:26:19
this is a really exciting space to watch and folks should folks should lean in and watch it.
00:26:24
>> Well, Sean, thank you so much for joining us today. It's always a pleasure
00:26:28
to have you. And um where can our listeners go to to keep up with what you're doing? Do you have a website or
00:26:34
or public facing side of Amgen so people can figure out, you know, how amaning into AI? Yeah, definitely. If you're
00:26:42
interested in either the science or the AI of what we've talked about today,
00:26:47
check out amjen.com. There's a bunch of great stories and teams there keep everybody up to date on what we're
00:26:52
working on. >> Okay. Well, that's great. Thank you very much. And that's all we have time for
00:26:57
today. We'd like to thank our producers, Aaron TR and Marissa Rena. And thank you
00:27:03
all for listening. We'll be back next week. Till then, this has been Marketing
00:27:06
Matters on the Wharton Podcast Network. I'm Barbara Khan here with America's
00:27:12
Reed. [Music]

Episode Highlights

  • The Essence of Marketing
    Americus Reed explains that marketing is more than just advertising; it's about strategy and science.
    “Marketing starts with science and ends with art.”
    @ 01m 09s
    October 24, 2025
  • The Role of Technology in Science
    Shawn Buick emphasizes the importance of technology in understanding complex scientific questions.
    “Technology is going to be really important in understanding the world.”
    @ 03m 41s
    October 24, 2025
  • Transforming Biotechnology with AI
    Shawn Buick shares insights on how AI can revolutionize medicine development at Amgen.
    “AI and data science have the potential to really change how we bring medicines to patients.”
    @ 07m 06s
    October 24, 2025
  • AI Adoption Challenges
    Shawn Buick discusses the difficulties of integrating AI into company strategy and culture.
    “How do you make the company strategy infused deeply with the DNA of AI?”
    @ 09m 27s
    October 24, 2025
  • AI Pilot Failures
    A striking statistic reveals that 95% of AI pilots fail to deliver value in companies.
    “95% of AI pilots in companies don’t generate value.”
    @ 10m 32s
    October 24, 2025
  • AI and Job Creation
    Exploring the potential for AI to create more jobs rather than eliminate them.
    “AI might even provide more jobs than less.”
    @ 21m 32s
    October 24, 2025
  • The Exciting Moment in Data Science
    A reflection on the transformative changes in data science today.
    “This is the single most interesting exciting moment that I’ve seen.”
    @ 23m 13s
    October 24, 2025
  • Democratization of Data Science
    Discussing how data science has become accessible to more people.
    “The power of data and algorithms has been democratized.”
    @ 24m 06s
    October 24, 2025
  • The Future of AI
    A call to pay attention to the evolving landscape of AI technologies.
    “Folks should lean in and watch it.”
    @ 26m 20s
    October 24, 2025

Episode Quotes

  • Marketing starts with science and ends with art.
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation
  • How do you make the company strategy infused deeply with the DNA of AI?
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation
  • 95% of AI pilots in companies don’t generate value.
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation
  • AI might even provide more jobs than less.
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation
  • This is the single most interesting exciting moment that I’ve seen.
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation
  • The power of data and algorithms has been democratized.
    How Amgen Uses AI & Data Science to Revolutionize Marketing and Biotech Innovation

Key Moments

  • First Week of Classes00:29
  • Introducing the Guest01:50
  • AI Pilot Discussion10:11
  • Breakthrough in Biotechnology17:51
  • AI Predictions19:51
  • Exciting Times23:13
  • Democratization of Data24:06
  • Future Insights24:53

Tension Over Time

Words per Minute Over Time

Vibes Breakdown