Search Captions & Ask AI

How Chamath Optimized His Health

November 17, 2025 / 12:31

This episode discusses health awareness, heart health, statins, and the importance of regular health screenings. Guests include Dr. Carlsburg, a leading interventional cardiologist, and Chamath, a biohacker.

The host reflects on personal health experiences, including the deaths of his father and friend Dave, which prompted him to prioritize his health. He shares his journey of understanding heart health and the role of statins, which he was prescribed by Dr. Carlsburg after discovering plaque in his arteries.

Dr. Carlsburg explains the significance of health tests like CT angiograms and their role in assessing heart health. The episode highlights the cognitive load associated with health testing and the importance of advocating for one's health.

The host visits a clinic in Silicon Valley, where they discuss advanced MRI scans and their impact on health diagnostics. He emphasizes the value of maintaining muscle mass and the need for regular health assessments as one ages.

In the conclusion, the host reflects on the journey of optimal health, emphasizing that it is an ongoing process rather than a destination. He encourages listeners to take charge of their health before issues arise.

TLDR

The episode emphasizes the importance of health awareness, heart health, and regular screenings, featuring insights from Dr. Carlsburg and Chamath.

Episode

12:31
00:00:00
I have so many of my friends that just literally have everything except their health and I just don't want that. You
00:00:08
know, there's a limited amount of time. I'm not trying to live forever. I'm just
00:00:11
trying to live well. So, this week I'm going to explore some questions that I have about my health and I suspect that
00:00:16
many people out there have about theirs. That's great so far. My father lived a really unhealthy life.
00:00:34
He struggled with alcoholism for decades. He was diabetic. He had heart issues. And in the end, he died of a
00:00:39
cardiac arrest. We were expecting his death, but he still left my mom, my siblings, and me, honestly, to pick up
00:00:47
the pieces. When my friend Dave died of a heart attack, I wasn't expecting it. To me, he
00:00:54
seemed perfectly healthy and that was my real wakeup call. We were in Mexico and he had a heart
00:01:02
attack and it was a real tragedy to be totally honest. But on the heels of that, his wife asked his four best
00:01:12
friends just to like really try to, you know, take care of ourselves better and specifically to start going and seeing a
00:01:19
cardiologist. Hey, welcome back. Thanks. It's great to see you. It's great to see you online on X, we
00:01:32
saw some uh interest about statins. So, Dr. Carlsburg, he is the best interventional cardiologist in the
00:01:41
United States. When he discovered some plaque in my arteries, he put me on statins. They're
00:01:45
supposed to lower bad LDL cholesterol, reduce the risk of heart attack, and stabilize plaque. But to some they are
00:01:52
controversial. Well, you posted basically trying to do something um for cardiac health across all of
00:02:00
America and you tagged me and Bobby, but the amount of commentary in Twitter or in X rather was all about the whether or
00:02:10
not I should be on a statin and whether or not it was just completely um pseudocience. Look, what I've learned in
00:02:17
my career is I could talk about anything. I could say the sky is blue and there will be opinions that say it's
00:02:23
not. So, to be honest with you, I kind of ignored most of it except to say that the few people who are very thoughtful
00:02:29
in there brought up, I thought, a very legitimate question. A lot of my followers feel like statins might help
00:02:35
them in some areas, but also hurt them in others. That's one of the reasons why I've been coming to Dr. Carlsburg so
00:02:41
regularly to help me figure all of this out. What's the most difficult part of doing all this testing, would you say?
00:02:47
To be honest with you, it's the cognitive load before you start it because I think there's so many
00:02:52
incentives. There's little voices inside of many people's heads that says don't even start because of what you could
00:02:57
find. And I do this test every four or five years called a CT angagram with contrast. It's basically a way of
00:03:04
injecting a die into your veins and then imaging your heart so that you can see all the arteries.
00:03:10
Breathe in. Hold your breath. What it's also able to do now is image it in such a way where you can take that
00:03:17
corpus of data and send it into a machine learning model and then now you can start to extract an even more
00:03:23
detailed sense of what's happening. That young lady is a perfect study. Absolutely beautiful.
00:03:32
I mean it's weird when the contrast goes in your body. Yeah. Um I've had it done a couple times
00:03:36
before obviously but I really I forget each time. The heart is important, but it's only
00:03:43
part of the story. If you want a more complete sense of your overall health, you really need a prenal scan.
00:03:49
Good morning. Hi, how are you? Good. How are you? Good, thanks. So, I reached out to
00:03:54
Chimath when we had just opened a clinic in Silicon Valley during CO and I thought I knew he was a bit of a hacker,
00:04:00
a biohacker, and I really wanted him to experience what we were doing. He was nice enough to come in. We developed the
00:04:06
friendship and he's been in for several scans. Click. You accept right there. In the 5 years since I met Chamath,
00:04:12
we've now imaged about 150,000 people. We've saved or made about 4,000 life-saving diagnosis. And every day we
00:04:21
get stories from folks where we might have saved their life or gave them clarity or delivered peace of mind. So,
00:04:26
it's really great to be building a company and at the same time having positive impact.
00:04:32
Okay, let's do it. So what makes us unique compared to others is we operate our own customuilt
00:04:38
research grade MRI hardware. We have AI that enables us to enhance image quality. And then we have this
00:04:45
incredible team of radiologists and medical professionals now over 100 that deliver a tremendous stand of care for
00:04:52
our patients. So I just did a full body advanced MRI scan. Took like an hour and 15 minutes.
00:05:00
But it really didn't feel that way cuz I just was lying in the machine watching Netflix. So, it's actually like a really
00:05:07
it's really great actually. Okay. Yeah. So, we just got in the car. We are uh headed to Toronto Tech Week.
00:05:16
Our first stop is at the Shopify headquarters for a fireside chat with my friend Farhan Thoir.
00:05:23
Good. How is the AI? [Music] What's up? Being on stage is something I like because it allows me to tell people what
00:05:35
I think is going on right now and what will go on. I hate to say it this way, but like the
00:05:40
more success that you can have, the easier it is to detach yourself from real life. And then you start to miss
00:05:47
out on people. And if enough people, you know, find that truth credible, some subset of
00:05:53
those people will self- select and say, "Hey, I want to work with you on this." And then I, you know, feed them into
00:05:58
those businesses. It's a great opportunity for them. But it's also how we get one step closer to achieving our
00:06:04
dreams. Now, we're going to jump in the car and uh go to the 8090 office and have lunch.
00:06:13
Yeah. Just trying to say hi. Good to see you again. Good to see you. Okay, let's talk because I don't want to
00:06:27
run out of time. So, what do we have till 3:00? What I found is that early on, especially when you're trying to do
00:06:36
something extremely ambitious like the 8090 team is trying to do, the biggest problem is drift. Meaning, you just kind
00:06:42
of drift away. Everybody just drifts away. they lose an understanding and I think the responsibility of the
00:06:48
CEO in that early phase when you're in a build cycle is to minimize the drift. The way that I think a good CEO can do
00:06:56
that is just reminding people of what they're there to do. And so, you know, in Toronto is just a chance to just take
00:07:03
everybody and sit them down, whiteboard something, just talk to them so that they could feel a sense of what was
00:07:09
happening. It's one thing to hear it on a Zoom or see it in slides, but it's another to just be in the room and feel
00:07:13
that connection. Super excited. Thank you guys. Okay, so what's the plan today? We're
00:07:23
going to go and get a little readout of the pre-nuvo scan. Um, and hopefully everything is, you know, relatively
00:07:30
straightforward there. These health tests may seem a bit like overkill, but I feel strongly that people need to
00:07:36
advocate for their health and ask a lot of questions. What we know is that you lose about 3%
00:07:41
of your brain volume every decade on average. Is that right? Yeah. And so the question is, how do you
00:07:46
compare? Honestly, my stomach fell a little bit when Andrew mentioned brain volume loss
00:07:51
because I knew the FDA label on statins warns about memory loss. All right, Sean, over to you. Tell me
00:07:57
the good news or the bad news. So, um, this is the enhanced scan now. And so, what what we're looking at here is just
00:08:04
blood flow throughout all the, uh, higher functioning brain tissue. And this is all very symmetric and normal.
00:08:09
Um, well, I think what Dr. London is saying is you're on a normal curve here. Suck it, people. All the all the haters
00:08:17
out there. Nothing worrisome, no change when it comes to my brain. I'm really relieved.
00:08:23
But something that did confound me is that I have some muscle loss, which is concerning. This is the main thing I
00:08:28
wanted you to to focus on and to highlight was the muscle the muscle mass because we know how important
00:08:33
maintaining muscle mass is particularly for you know brain health too over time and it's harder to maintain as we get
00:08:39
older. Plus the internet internet thinks that I don't work out that I should be doing
00:08:43
more leg day. So this is going to really feed the whole conspiracy. I mean take everything with a grain of
00:08:48
salt too. You know like they're going to love it. I mean it it's not like a a terribly
00:08:52
concerning decrease. Yeah, it was just it was just more notable than the than the other uh fluctuations.
00:08:58
But the trolls are going to love it. Like I told you, you don't work out your legs.
00:09:02
It's not true, guys. I'm just tall. I mean, every time I come, it just gets a You're doing a better and better job
00:09:08
building this thing. It's so great. I love being a guinea pig for stuff like this.
00:09:12
Yeah. And it's been really valuable for me. The next like 10, 11, 12 years. I really
00:09:17
want to make sure I pack as much muscle as possible. Insulate myself going into my 60s and
00:09:21
70s. Seems like the right goal. Thank you. Thank you very much. Thanks for visiting.
00:09:25
Great to see you. Yeah. Now it's time to check back in with Dr. Carlsburg and face the music on my
00:09:31
heart. Welcome back. Thank you. Good to see you. Uh you had a really busy day yesterday,
00:09:38
didn't you? Busy day, but a good day. What I'm going to do now is present something that's quite astonishing. You
00:09:45
have a zero calcium score and you still have a zero calcium score. Let's get out of here.
00:09:52
Not so fast. We see that over the 10 years you had a 370% increase in that material, which means
00:10:04
that you are on a pathway to atheroscerosis, but you're one of the few peoples on the
00:10:10
planet that have this kind of information and you're going to take advantage of it. And so what we're looking at here
00:10:17
was a percent change that went from total plaque volume fell from 24% a year to 10% a year, which is consistent with
00:10:27
what we found in much bigger studies. Now, given the first level of tears, which is listen to your audience and
00:10:36
come off the drugs because they're dangerous, or stay on the drugs, the first level of decision on your part
00:10:43
based on what you heard is going to be what? Obviously, we're going to stay on the
00:10:46
drug. So, okay, that's your decision. Yeah. Okay. I think what I'm hearing from you is
00:10:53
we started this statin a decade ago. It seems to have had a pretty meaningful impact. we
00:10:59
in all of these other things that we never would have known to look for had this stuff not existed.
00:11:04
Exactly. So, what I'm learning from you actually is a big deal. You've done some good
00:11:07
stuff and that was actually pretty preventative and good, but there's now an even better leading edge for you
00:11:14
because you're fighting against a genetic trend that will eventually catch up with you.
00:11:19
It that's a secret. That's fantastic. I want to know the secret. I want to know the answer. Now,
00:11:24
there are no standard treatments for you. I think that you could choose to wait. Your calcium score is zero. Your
00:11:33
outcome is going to be fine for the next 5, 10 years. Chances of you having a cardiac event are very, very close to
00:11:40
zero. No risk of a cardiac event in the next five years. Hopefully 10. Uh that's my prediction. All right.
00:11:48
You're doing a great service. Thank you. Thank you. See you soon. Have a great summer.
00:11:51
Byebye. You know, if there's one thing I've learned through this process, it's that
00:11:56
there's no finish line. Honestly, optimal health isn't a destination. It's a journey. But at the end of the day, we
00:12:03
all face the same choice. Do we wait until something breaks or do we start listening now? Starting the health
00:12:09
journey can be scary. But in my opinion, I think it's worth it because living well is the best return there is.
00:12:15
Well, we're home. It's been a long week. I hope you enjoy following me around, but now it's time to get the out of
00:12:22
here.

Badges

This episode stands out for the following:

  • 70
    Most shocking
  • 70
    Most surprising
  • 60
    Most inspiring
  • 60
    Most intense

Episode Highlights

  • Heart Health Insights
    Discovering the impact of statins and the importance of regular health checks.
    “You have a zero calcium score and you still have a zero calcium score.”
    @ 09m 48s
    November 17, 2025
  • Health Journey Reflection
    Exploring health questions and personal experiences with loss and health advocacy.
    “Starting the health journey can be scary, but it's worth it.”
    @ 12m 07s
    November 17, 2025

Episode Quotes

  • I'm just trying to live well.
    How Chamath Optimized His Health
  • There's no finish line.
    How Chamath Optimized His Health
  • Living well is the best return there is.
    How Chamath Optimized His Health

Key Moments

  • Health Advocacy00:14
  • Personal Loss00:49
  • Statin Controversy01:52
  • Cognitive Load02:48
  • Health Scans04:58
  • Positive Diagnosis09:48
  • Ongoing Journey11:58

Tension Over Time

Words per Minute Over Time

Vibes Breakdown