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The Ozempic Expert: Ozempic Transforms Your Gut Microbiome! People Are Being Overdosed On Ozempic!

July 04, 2024 / 01:58:04

This episode features Dr. Tina Moore, a naturopathic physician, discussing the benefits of microdosing GLP-1 agonists like semaglutide for various health conditions. Topics include metabolic dysfunction, chronic pain, and the impact of lifestyle changes on health.

Dr. Moore shares her personal journey with chronic pain and how she discovered the potential of GLP-1 agonists to improve her health and that of her patients. She emphasizes the importance of addressing root causes of diseases rather than just symptoms.

She explains the differences between traditional allopathic medicine and naturopathic approaches, highlighting the significance of treating individuals holistically. Dr. Moore also discusses the alarming rise in metabolic dysfunction and its implications for fertility and overall health.

Throughout the conversation, she provides practical advice on lifestyle changes, including the importance of strength training, nutrition, and sleep for maintaining metabolic health.

Dr. Moore encourages listeners to seek knowledge and be proactive about their health, emphasizing that small changes can lead to significant improvements over time.

TL;DR

Dr. Tina Moore discusses microdosing GLP-1 agonists for chronic pain, metabolic health, and lifestyle changes to improve overall well-being.

Video

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this is not what they're telling us we can start to heal some of these chronic lifestyle conditions that are so rampant
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with tiny doses of this it's like opening a window of opportunity for somebody to completely change their life
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Dr Tina Moore is a distinguished naturopathic physician whose groundbreaking work is leading the way
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in combating some of the biggest diseases in medical conditions that our modern world currently faces everyone's
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saying that OIC is evil this is the worst thing ever but a lot of people are being overdosed for weight loss and this leads to a very high risk for side
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effects but o done correctly has all these other benefits that have nothing to do with weight loss and they are just
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mind-blowing healing and reversing type 1 diabetes Parkin and Alzheimer's we've got studies showing really positive
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impacts on depression and anxiety and potentially reducing cancer risks it shifts your gut microbiome to a more
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favorable microbiome and then my daughter PCOS symptoms reverse which is probably one of the number one drivers
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of infertility in young women I mean holy sh and I've seen it with my patients and I've seen it with myself
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cuz I lived with chronic pain my whole life and I Remember by the end of 2021 thinking if this doesn't get better I
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think I'm going to kill myself but I started myself at a tiny little dose and the destruction fell
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away Dr Tina Mo what would you scream to the world right now we are eating a chemical storm of a food supply young
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women are bathing in toxic chemicals through their beauty habits microbiome disruption from all the antibiotics I
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joke that humans are going extinct but I think it's really happening if we don't write this ship but there's things we can do that are non-negotiable that have
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nothing to do with drugs your six pillars for a pain-free life yes first of all I would congratulations diio gang we've
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made some progress 63% of you that listen to this podcast regularly don't
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subscribe which is down from 69% our goal is 50% so if you've ever
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liked any of the videos we've posted if you like this channel can you do me a quick favor and hit the Subscribe button it helps this channel more than you know
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and the bigger the channel gets as you've seen the bigger the guest get thank you and enjoy this
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[Music] episode Dr Tina
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more who are you by profession
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and what is the mission that you're on so I'm a naturopathic physician and a
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chiropractor I don't know if you have naturopathic Physicians here in the UK we are trained formally in a four-year
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medical program and we take national board exams North American I should say
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and we are taught root cause medicine so the functional medicine Community basically appropriated our medicine many
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years ago if you've heard of functional you've had doctors on there are functional medicine practitioners and
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it's the idea that the body can heal itself we are looking to restore homeostasis in the individual so why are
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things arai I'm less interested in someone's diagnosis as much as I am why are they presenting with that symptom picture what's going on and I was
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mentored up by one of the finest naturopathic physicians in our profession over the past many decades
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and he died of cancer in 2013 and I took over his practice he was a force to be
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reckoned with so I carry that flag with me and he was a truth tell and he
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was often ostracized by our profession for being ahead of the game and you know
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being ahead of the story usually and I learned so much from him about metabolic
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health and how metabolic Health was really the root cause driver of so many diseases life style induced diseases
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that we're seeing in on a worldwide level can you give me just a bit of a glimpse and for someone that's never heard the term naturopathic physician
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before which which I guess means naturopathic doctor right what is the
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difference between like a normal doctor and a naturopathic doctor so a
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traditional allopathic physician is what you're going to be familiar with with an MD they're trained in a system where
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algorithmically they are taught to find disease processes and then they have a stand of care that they follow which is
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to prescribe X Y and Z yeah for the standard of care and that's not how they always were naturopathic medicine was
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born out of old timey European MDS so back in Germany and you know long time
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ago when we didn't have all the fancy lab tests and we didn't have all the fancy Pharmaceuticals we were treating
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people to bolster their health really you know it's taking you as an individual finding out what makes Mak
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you tick and then how can we optimize your health overall symptoms and illness Falls away when you treat the body when
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you treat the individual in front of you so I don't treat diseases I treat people that's the difference whereas in
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allopathic medicine they are very obsessed with
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the diagnosis and then what pills do we apply to that diagnosis which is different than why is
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this person presenting this way and what can we do to help them along the Journey
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of optimizing their health so those symptoms fall away and you you said you took over a clinic there yeah what kind
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of patients do you see in that practice did you see in that practice and what was the sort of variety of illness or
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disorder or disease that you came across so his practice was predominantly muscular skeletal medicine so it was uh
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chronic joint dysfunction and he did a specialized type of medicine called Prolotherapy and regenerative injection
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therapies the modern version of that is stem cells you've probably heard of stem cell injections I'm sure everyone has by
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this point plate rich plasma is another one and that's what he specialized in but it's not just about shooting fancy
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substances into people's joints you have to get the person into a healing State first so you need them optimized so that
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they want to heal so that means hormones that means nutrition that means lifestyle those things are far more
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critical to get lined up than it is to start shooting fancy substances into
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their joints even if those substances come from their own body even if we're sucking out their own stem cells and we're sucking out their own blood and
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we're using those it's far more important that you get the person in an optimized state so that they want to
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heal so I you know I'd ask patients if you cut your fingertip off or just sliced yourself terribly do you heal
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well and if they said yes they were a wonderful candidate for those types of injections if they did not then they
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weren't because they weren't in a good healing State at that point so my job was to get them in healing State and
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then to apply the treatments what is a healing State it's when you fall down
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and you don't fall apart it's when you get sick with something and you get over it it's when you cut yourself and you heal readily and you don't you know
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succumb to terrible infections and I think we've ended up as a society where the norm has become to be
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somewhat imuno compromised I think a lot of people are walking around not not you younger folks but at least in the US a
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lot of people are walking around in this sort of semi imuno compromis State much of it is due to metabolic dysfunction
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which is something he was always drilling into me what is metabolic dysfunction it is when
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your metabolic Health at its core is the ability to take in the foods that you
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eat and assimilate them properly so if you were to eat proteins and fats and carbohydrates you would turn them into
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the fuel that they need to be you would turn them into the proteins in your body that they need to be when that goes Ary
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which is almost 100% of us adults at this point from what the data is showing
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things don't go so well and so what that leads to this metabolic dysfunctional pattern leads to insulin resistance
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which is essentially pre-diabetes which is the long game into di type two diabetes and we've completely normalized
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that process at least during my lifetime I've watched that happen I'm 50 years old so I've watched this happen
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especially since I got into medicine working for my mentor Dr Rick watching folks go down this pathway of
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normalization into type two diabetes and it's not until they get there that the doctor says oh you have type two
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diabetes we got to do something about it here's your pills and there's 15 to 20
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years of leg work that can be done before that happens and that's where I think naturopathic medicine really shines and where preventative functional
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medicine all of us are in the same camp we're all doing the same thing we're really trying to just help the patient in front of us not so much the disease
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process we're trying to make sure that the person's optimized so that they can become more resilient so that their
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immune system works properly so that the foods that they eat are assimilated properly and they don't end up in a
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cellular millu of disaster is is there like a fundamental belief that you have
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about human beings how we heal how to be healthy um and the body I guess that you
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think is in contrast or conflict to the current system like a set of fundamental underlying beliefs because we all have
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like a set of sunglasses on our lens of how we see the world yes and what I've obviously learned from doing this
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podcast is everyone seems to be wearing slightly different lenses M you know as
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to their view on health this the healthare system humans healing Society
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what are those sort of fundamental underlying beliefs that you have that's a great question I think that in
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traditional naturopathic medicine the purist would tell you that there's no room for pharmaceuticals and that you
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must only go with nature the healing power of nature stoke the individual's
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Vitality that's very important in naturopathic medicine we're looking at the Vitality of an individual some would call that an aura I think
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that's a little too esoteric it is when you look at someone are they are they
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glowing Vitality do they look healthy you can see it I know you can everyone can see it when you actually point it out to people do they look healthy or
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are they sort of walking around in grayscale right and I think a lot of people these days are unfortunately
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walking around in grayscale because they've sort of you know we've all been listening to the mainstream narrative
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and the food suppli is busted this has been going on for decades my mentor was talking about this decades ago nobody
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was listening and now people I think are starting to get hip to it because we've got the internet we've got podcasts like yours and mine where we're trying to get
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the you know the information out and it's the inherent ability of the body to heal however I do think there's a place
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for pharmaceuticals and I have a license to prescribe in the state of Oregon and I'm not afraid to use it because in my
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mind and the way that my mentor taught me is somebody comes in and they're on this many Pharmaceuticals I mean I'm 50
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the average person my age is on five different Pharmaceuticals at this point which is crazy to me and I don't know
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what the stats are in the UK but I can't imagine they're tremendously better so they come in on all these drugs and their lifestyle is in somewhat of
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shambles and so my job is to optimize lifestyle so that I can get these down to the lowest or to nil ideally we could
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get them off but if they need a little something then great I was also taught by him to implement longevity medicine
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which is hormones and making sure that people are able to maintain physiologic levels of optimal hormone function as we
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age which is really important to aging well and so it's just kind of a mix of using the best of Nature and that
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science has to offer and treating the person in front of you of all the case studies that you have in your mind
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experience and in your past is there one that you are most PR of it was
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2019 my career was really taking off and my mom kept telling me that she didn't feel good and I was like my mom is a
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rock my mom's my mom's like comes up to he on me I call her my little mama and she just chugs along and I was like oh
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she'll be fine she's like no I really don't feel good and I kept blowing her off cuz I was too busy and I was on
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planes all the time and traveling all the time and I was never home and my mom came to visit me at my house and she
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came out of the bathroom and she said she's like I like I can't hold my bowels like I I
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can't I'm so sick and so I immediately started testing her and she had Crohn's
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disease and my grandmother had died of Crohn's Disease and several people in her side of the family had died of Crohn's Disease and I just hadn't put
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two and two together that my mom may have had but she had all the symptoms like growing up she had all the symptoms and I just never put it together and it
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was hitting her it it rears its ugly head when folks hit their Elder years like in their 70s they call it you know
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colitis of the elderly and people basically get it and die they just [ __ ] themselves to death and so my mom was in
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it and I was like oh no and I pulled out everything I had and I have access to
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some incredible regenerative substances that you know most people don't and I can use them off
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label in ways that you know in most people don't even think to do and I
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threw everything I had at her because I knew if I'd sent her into the alpath system they were going to do a
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colonoscopy on her and what that does is they flush you out before they do the colonoscopy and if I if her Flora were
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to get flushed out of her gut at that point I don't think she would have come out of the hospital because they end up getting secondary infection
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and so I I pulled her out of it I got her out of the really acute phase and then I immediately referred her to my
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colleague who is a brilliant physician naturopathic physician and I was like take over I'm not I don't want to manage my mom but I needed to get her I I knew
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that it was the skill set that I had in particular that was going to pull her out of that and so we did it and she
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came to me one day after she was better and she was stabilized and she said you saved my life and at the time I was
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really bitching about my half a million dollarss of student loan debt that was just compounding and compounding and
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compounding and I was really frustrated by the fact that I couldn't get on top of it and I had at that point spent like
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$100,000 paying off my loans and they were still at the same level I mean it just criminal that system and she said
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you saved my life it was worth every penny you know and then my daughter turned around who had just gone through a very difficult time herself and she
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said you saved my life too Mom this year and I was like well that was what it cost to gain
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the knowledge that I gained to save my daughter and my mother and then my dad was like you saved my You' bailed me out
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many times and I was like okay that's so it was kind of um it was just kind of
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ironic that was the end of my big clinical career you know when I had my big brick and mortar with the high
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volume patient base and all of I still see patients but not at that level and so that was
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really I was like thank God I had the knowledge and the tools and the knowhow to and the fearlessness to apply some of
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the therapies that I applied the way I did to in terms of before and after what sort of picture of Health would I
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observe if I saw her on that day when she walked out of the toilet versus you know after the the variety of different
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therapies that you applied well this is a good story because she was super gray and super thin and my mom has always
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been kind of you know hippie and curvy and I mean she's we're built different she's she's the more you know um she's
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the curvy one and she was just ra thin and gray and all of her hair was falling
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out I mean she just I can't believe I missed it I can't believe it went on that long that I didn't see it and I I still carry guilt to this day and I
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always apologize to her for being too busy to I can't believe I let my stress level get so high that I didn't see it
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you know and then she ended up on a slew of pharmaceuticals that were too expensive
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to get in the United States so she had to get them from Canada so her naturopathic physician is managing her so she's getting medication very
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expensive medication from Canada and she's doing okay and then in the last nine months I put
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her on the tiniest droplet of seacu tide which is a zic and she is phenomenal all
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of her joint Pain's gone her guts completely regulated and normalized she is down on a minimal dose of this
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medication that she's getting from Canada she's still taking it but it's a tiny dose her cognition has improved significantly because through this
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process she was starting to get low-grade dementia whether she realizes it or not my daughter and I were noticing it we were like is Grandma okay
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and so when people come at me for talking about micro doing OIC I will not
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back down because my mom is solid and it's the tiniest amount and she even
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said to me just the other day before I was coming on the show I was telling her I was stressed I was trying to get ready for the trip you know overseas and she
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said you know I was so stressed out before you put me on seacu tide because my dad's health is very poor and she
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said I was so stressed that I really felt like it was going to do me in like I was at capacity and you put me on this
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acuti and all of the anxiety and stress just dropped away and I was like that's
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cuz it's calming to neuroinflammation which is secondary to Chronic
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gastrointestinal diseases when the gut is inflamed the brain's inflamed so she was dealing with all this chronic brain
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inflammation all this gut inflammation and she's on this tiny little dose of OIC and she's very solid and she's her
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color's back she's filled in again she's curvy again she's eating normally she
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does I mean she couldn't eat hardly anything ever for years and so now she's back to eating very normally she's still
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got to watch what she eats but you know it's not a free-for-all but she is she's back the other I guess glaringly obvious
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case study for your work but also I think many of the things we're going to talk about like micro doing and zenek is
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you yeah because as I read through your story from your childhood years through your teenage years and even in
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University um and then even later into your career and I guess also now because you mentioned that you still deal with
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chronic pain you are your own case study I am
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can you give me a view of of the struggles you've been through in terms of your health um and really where that started what was the sort of first first
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instance where you experienced the pain the trauma etc etc so I always had stomach AES always since I was a child
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always and was hit with really pretty severe anxiety I didn't know what it was
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at the time but it was anxiety and and I started getting chronic pain in my
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teenage years and I out of nowhere when I was about 15 the lights went out on me
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I just became extremely suicidal and depressed out of nowhere I mean it was like somebody just switched a lever I
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had moved to Oregon from Southern California I do believe that the lack of light was massive I think that people
00:18:21
really I'm really starting to appreciate it's taken me all these decades but light deficiency is a huge issue that
00:18:27
we're not no one's talking about if few people are but you're talking about like vitamin D production as well right there
00:18:32
because there oh that was huge so that took years you know nobody was talking about that it was not until decades later I was sitting in naturopathic
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medicine school I was in college and um I think I was in year three of that program and this doctor Dr Alex Vasquez
00:18:46
came to lecture at Ground rounds and he started talking about vitamin D and sunlight deficiency and I had been kind
00:18:52
of low-grade looking into sunlight deficiency because it turns out the hospitals of your really would optimize
00:19:00
sunlight and they would have sun porches I don't know if you've seen the photos they would roll all the kids out and all of the convalescing ill people out I
00:19:06
mean that's how people survived the 1918 flu was the ones who got sunlight and the ones who were able to go to these
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hospitals and they would build the hospitals to optimize light exposure inside the board because they knew it kept the bacteria counts down and I mean
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even if they didn't know what bacteria was or what was happening they knew that when sunlight penetrated people were you
00:19:25
know healthier and things were cleaner and infections didn't seem to spread and so I hit my 20s and long story short I
00:19:32
was rocking psoriatic arthritis for decades before I ever figured it out and it really culminated for me I went
00:19:39
through a lot of chronic pain I went through a lot of misery I went through a lot of autoimmune issues and then I got everything dialed in I thought I had it
00:19:45
handled interestingly autoimmune disease will flare and will recede and flare and
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recede and it's kind of on Q like you'll see it around 10 to 11 years old especially with things like Crohn's
00:19:57
disease you'll see these little glimmers pop up for kids and then it goes away and then you'll see them present in
00:20:03
their teenage years and often they'll present with you know mental emotional issues and not so much the gastrointestinal issues but it's the
00:20:08
same process going on in the body and then it'll go away and then it might flare again postpartum because of that
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big hormone surge that happens with child birth and then it'll go away and then it'll come back with a vengeance in
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menopause as the hormones again shift majorly and that's what was happening for me and then all of the stress of
00:20:26
pushing Back Against The Narrative really caught up with me and I was
00:20:31
nothing that I knew to do was working so the whole protocol I put my mother through was not working for me nothing
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was touching it and that is how I came to start studying glp1 Agonist I started I was researching anything that would
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calm neural inflammation because at the end of the day diseases down here are
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coming from here and when the brain's on fire and the brain's inflamed the immune system gets sent completely sideways and
00:20:57
the Downstream processes culminate in autoimmune disease pain hormonal
00:21:03
disruption you name it and so I that's how I ended up I literally put into
00:21:09
Google glp1 and neuroinflammation and all these studies showed up and that's
00:21:14
what got me going two questions there so glp1 is a zmek so it's yes it's the
00:21:20
peptide that the body makes naturally we make it in the brain and we make it in the gut but if somebody's had a life of
00:21:27
chronic gut inflammation I don't think they're making it so well in the gut and
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OIC is just a it's several versions down in the generational line of these
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peptides called Inc cretans they're um they're a whole family that started way
00:21:44
back 20 some years ago and they've just gotten a little bit nicer with less side
00:21:50
effects and longer halflife as we go along the journey so the last decent one
00:21:55
was Lorac glutide although compliance was low because it made people feel really terrible and they had to inject
00:22:01
it too frequently I think it was daily or I think that's how it is still and then seacu is a newer generation tepati
00:22:07
is a newer generation and so they're they're just getting a little more potent and I don't mean potent in a
00:22:13
pharmaceutical way I mean they're starting to realize how these work and they're they're getting craftier with
00:22:19
not only keeping them in the body for the time that they need so the halflife gets longer but they're finding in this
00:22:24
Suite of signaling peptide hormones that are involved with app appetite and with
00:22:29
metabolic health and Insulin secretion and insulin sensitivity they're finding better and better ways to combine these
00:22:37
to get optimal function with the least amount of side effects okay and at that
00:22:43
moment in your life where you started Googling glp1 and inflammation
00:22:49
Etc if I was a fly on the wall in your life at that moment what
00:22:56
would I have what would I have seen what was the sort of picture of desperation
00:23:02
or you know so 2021 I spent most of that year on my back cuz I was in so much
00:23:07
pain it was crazy and my husband when he met me he met me in 2019 and we got married in
00:23:13
2020 and I told him I had chronic pain and I told him I had a funny immune system but he had never seen it like
00:23:18
he'd never seen it full force and he got to see it that year he was like wow so this is what chronic pain looks like I
00:23:24
mean it's it was devastating and my spine was fusing and I'm active I do platies and I dance a lot and I hula
00:23:30
hoop and I roller skate and I lift weights and I'm you know moving and shaking I was not moving and shaking in
00:23:36
2020 I was 2021 I was flat on my back on the couch and I Remember by the end of 2021
00:23:42
thinking if this doesn't get better I think I'm going to kill myself
00:23:48
like I couldn't do it anymore like I just couldn't live with that level of
00:23:54
pain and my spine was fusing and I could feel it and I kept trying to tell everyone something is wrong and my chiropractor friends were
00:24:01
great but they knew muscular skeletal medicine and my naturopathic friends were great but they knew systemic medicine and I I needed me I needed my
00:24:07
brain on the case like someone who had both right and I just couldn't get on top of it and then finally I I don't
00:24:14
know how or why I I went kind of into the story oh I know what it was I broke out with psoriasis I broke out with
00:24:19
psoriasis all over my scalp and I was like oh this is what this is this is ptic arthritis which turns out to be one
00:24:25
of the most painful muscular skeletal autoimmune conditions you can have it it's worse than rheumatoid arthritis on
00:24:31
the Pain Scale from what the studies shows so I was like okay now that I know what I'm dealing with what can I do so I
00:24:37
started pulling out all the stops and all the things I knew to do lotos now trone exomes you name it I was doing
00:24:44
everything it really wasn't bringing it down or it would work for a minute and it would it would it would wear off and
00:24:51
so I was getting desperate and my I have a podcast and my podcast producer said you got to do an episode on OIC and I
00:24:57
was like I don't I don't like talking about weight loss I really don't like talking about weight loss it people get so emotionally
00:25:03
triggered and it's a big topic and it's nuanced and it's not as simple as people
00:25:10
want to make it be and in my functional medicine world people want to make it so simplistic just exercise more and eat
00:25:15
less and take these supplements and it'll go carnivore and it'll all go away
00:25:20
it's not that simple there's genetic components there's brain components there's epigenetic components and it was
00:25:26
like the Pandora's Box I didn't want to open and so finally I was like okay fine I'm going to start researching these and
00:25:33
I was sitting I was laying on the couch on my back and it's 2023 at this point but I'm still having to take frequent
00:25:39
breaks right on my back so I'd go exercise and I'd have to lay down for three hours so I'm Googling and I look
00:25:45
up glp1 and neuroinflammation because I always start there I always start with pain
00:25:51
neuroinflammation and immune activation I always want to know what any substance does in those because that's my world
00:25:56
right because that's what I did in clinical practice and I googled that my husband's in the kitchen and I was like holy [ __ ] and I
00:26:05
turned the phone around and I was like look at this and he's like I don't know what that means babe and I was like this is not what they're telling us like this
00:26:12
is not what because that was at the height of mainstream media and all the clickbait headlines and you know Mom is
00:26:18
overdosing on OIC and people's stomachs are paralyzed forever and I was like so
00:26:24
then I started of course looking at all that like is that for real like are they really getting gastroparesis forever no
00:26:31
so I start going into all the data and I just that was it it was like the rabbit hole and it that was May of 2023 and
00:26:38
I've been kneee in it ever since just consumed by any and all information and
00:26:44
then of course everybody start I started doing podcasts about it on my show and everyone's sending me all the
00:26:49
information and hundreds of people are reaching out to me telling me these really profound stories and changes in their health that have nothing to do
00:26:55
with weight loss or diabetes and so that was it I was like I got I got bit
00:27:01
by some kind of um well you know I don't like propaganda I don't like when I hear
00:27:07
everybody saying the same thing it makes me suspicious you know when everyone's running in One Direction screaming this
00:27:15
is evil this is this is this is you know the worst thing ever I was like I don't
00:27:20
know this has been around for 20 some years not some acuti but this version of medication this family of medication and
00:27:27
so I don't know I was like I'm not buying this I'm gonna find out what the truth is and so I called every doctor I
00:27:33
knew that might use it I called every pharmacist I knew that might use it nobody was seeing any of these
00:27:39
horrific side effects like the stories you were seeing on the media currently what was that summer that was really it
00:27:46
came to like full height summer of 2023 I think that was when everybody was losing their minds about it the minute
00:27:52
they started talking about weight loss people started losing their minds about it which I find very interesting and
00:27:58
what I was Finding in the literature was not at all adding up to what I was
00:28:03
hearing and then there were all of these other benefits that were just mind-blowing you know benefits on
00:28:10
healing and reversing type 1 diabetes healing and reversing neurocognitive
00:28:17
conditions like Parkinson's and Alzheimer's efficacy with alcohol sensation people who were you know
00:28:24
alcohol abuse syndrome using it for that people who also o had the this type of
00:28:30
hlb27 it's a genetic propensity towards these um spondo arthritis is like
00:28:37
psoriatic arthritis rheumatoid arthritis those kinds of things having showing efficacy for that and as I started
00:28:44
speaking out about it I was getting messages back from people telling me their stories hundreds
00:28:50
and hundreds of people telling me their stories and I and then seeing what was happening with my patient so I started applying it to everyone I was treating
00:28:56
for different reasons at different doses very tiny doses though very little bits
00:29:02
and just seeing really profound changes in people and I it's not what we're
00:29:07
hearing and I don't think that the way also that it's being done in the standard model
00:29:13
is ideal for everyone I think a lot of people are being dosed too high too fast and I think a lot of people are being
00:29:19
overdosed because at the end of the day it's a hormone it's a peptide signaling hormone and so people are being cranked
00:29:24
up on doses very quickly there's a 16 we escalation and they go from this amount to this amount very quickly and in the
00:29:33
journey many people are reporting horrific gastrointestinal side effects which are real but it's not the
00:29:39
peptide's fault it's the it's a peptide at the end of the day as well which is I can explain what that is yeah if you had
00:29:44
to explain what a zmek is or W go or you know this this compound is just to a
00:29:50
10-year-old yeah okay how would you explain it so you eat amino acids you
00:29:55
eat protein and it breaks down into amino acids yeah and amino acids link up with peptide bonds into chains called
00:30:01
peptides and then peptides a peptide bond uh it's just a simplistic bond that
00:30:07
binds two amino acids together so it can be broken pretty readily with different enzymes and that's in my body the
00:30:13
peptide bond is in my body yeah so your body has all these enzymes present and the amino acids link up very
00:30:20
simplistically into different chains and then those chains of amino acids are called peptides and peptides link up to
00:30:27
form proteins and your body is made of proteins your whole body all of your tissue is made out of proteins and your
00:30:34
cellular receptors are made out of proteins everything's made out of proteins so if you go backwards those
00:30:39
smaller versions are the amino acids I'm sorry are peptides and the smaller versions of that yet are the amino acids
00:30:46
so we eat protein we break it down into amino acids and we reconstruct it into more protein and so peptides are these
00:30:55
chains of amino acids that we've got all different typ of therapeutic peptides and they insert themselves where they
00:31:00
need to go to do what they need to do so that's it at the end of the day and what
00:31:05
so what's a zek in that is zek is a peptide it's a peptide and it's made in
00:31:10
our L cells of our gut which line from the most proximal to the disal small intestine and it SEC these cells secrete
00:31:19
glp1 in the presence of glucose which is sugar when we eat sugary Foods or food
00:31:25
well all carbohydrates break down into glucose so whenever we eat glucose and they respond actually when a bolus of
00:31:32
food so the mechanism of a blob of food going through our guts actually gets
00:31:37
these cells to trigger however I have tested thousands of people's guts in my clinical practice
00:31:43
in my clinical Lifetime and people's guts are a mess most people have compromised digestion so I don't think
00:31:50
their L cells are working optimally in many cases and we also have literature
00:31:55
good solid science to show that those who are suffering with obesity type 2 diabetes and fatty liver and that whole
00:32:01
metabolic syndrome you know groupage those folks are glp1 deficient so when I take a zmek
00:32:09
it's causing my gut basically my body to release glp1 No it is the glp1 oh it is
00:32:17
the glp1 yep so we're not causing the gut to do anything we are mimicking the actual peptide okay so it's got the same
00:32:24
sort of atomic structure as AAL so my body thinks it's gp1 I guess it is G as far as things are
00:32:30
concerned and then the gp1 is doing what to me well so it's STi for instance Is
00:32:36
bioidentical to the glp1 that our body secretes so it's the same except it's
00:32:41
been tweaked with a little bit they've added some lipids to it to make the halflife longer so it lasts longer so
00:32:48
normally glp1 would be secreted from our cells it's also secreted from our brain which we got to get into because that's
00:32:53
where I got really excited it's secreted from our body and it's broken down very quickly and so these newer versions of
00:33:01
these incretin hormones or incretin peptides are broken down at a slower
00:33:07
Pace okay and then what does glp1 do it does all kinds of cool things so
00:33:15
it most notably in what it's known for is to decrease appetite and that happens
00:33:21
centrally in the brain yeah it slows gastric motility so it slows things down
00:33:26
so you feel Fuller for longer that's at higher doses that doesn't always need to happen and that is what it is known for
00:33:33
and it also has induction of it it plays with the cells of your pancreas and it
00:33:39
gets them to secrete insulin at the right time and so most folks are walking
00:33:45
around in some degree of insulin resistance as they age and that is the beginning glimmers of type two diabetes
00:33:51
and so gp1s help that process it helps sensitize the cells to the insulin and
00:33:57
it helps treat the insulin when needed and when you were struggling in
00:34:03
2023 yeah you started taking a zmek SM magti one of these Brands yeah
00:34:11
um what impact did it have on you so I got a compounded version
00:34:17
because I thought that the starting dose let's back up the brand name the prescription that most people are
00:34:22
familiar with are these little pre-filled pens yeah and the pens only come in certain doses you can't control
00:34:29
the dosage you start at the lowest dose that they offer and then you have to escalate from there or if your doctor's
00:34:34
cool they won't make you escalate too much but either way you don't get to go lower than the dose that it starts and it starts at 0.25
00:34:40
milligrams I thought that that was way too high especially for someone like myself I'm very metabolically optimized
00:34:46
I have good muscle mass uh I have very good bone density I have my labs look beautiful I'm hormonally optimized I'm
00:34:52
on bioidentical hormone replacement I'm very active I exercise often my sleep is good
00:34:58
and I thought my thinking was I wonder if some of us are actually a little glp1
00:35:05
deficient from whether a life of not because we have obesity diabetes
00:35:10
and fatty liver there's different reasons why those folks would be deficient insulin at high levels itself
00:35:16
will actually induce some glp1 deficiency it'll it'll decrease glp1 signaling my thinking was I wonder if
00:35:22
folks are just genetically or maybe we got ourselves there through chronic illness
00:35:28
whatever it may be I wonder if there's a little bit of a deficiency what if I supplement this peptide like I would a
00:35:33
hormone which the way I do that is I give people the lowest dose necessary to
00:35:38
achieve a physiologic impact that's favorable and then I cap it so if you need a little bit of thyroid the
00:35:45
standard model would have you take well you know the algorithm says you have hypothyroidism so we're going to give
00:35:50
you this much and we're going to be this exact drug in my world we compound what we need maybe you need a little more T3
00:35:56
than T4 Maybe you need a tiny dose maybe we titrate you up until you start getting a little symptomatic and we're
00:36:02
like let's back it down a little so my thinking was to use it that way so I asked everyone I knew are you using this
00:36:08
for anything other than appetite suppression or weight loss or diabetes and they all said no nobody really was none of my colleagues were anyway and
00:36:15
they were all starting at a dose that I still thought was too high so I started myself at a tiny little dose and my first impact was brain
00:36:23
Clarity within days my brain cleared I can't even explain it um brain fog was
00:36:29
definitely starting to happen I think it was the psoriatic arthritis and I think it was the I think it was postco you
00:36:35
know I think our brains all got hit pretty hard by that and I think it was chronic stress and I think it was
00:36:40
menopause and I was sort of in this I'm a high functioning kind of Boss babe and I couldn't get my work done and my team
00:36:47
was going crazy because I couldn't remember what I told them and you know they're calling me and they're like we already did this we already had this
00:36:52
conversation what is wrong with you so I was like damn it this isn't going to work for me I can't rolling the way I'm
00:36:58
rolling and trying to run all my businesses and have brain fog like this so that was the first thing I noticed
00:37:03
was Clarity of thought brain fog went away anxiety immediately dropped which I didn't even realize I had it just a
00:37:09
calmness took over me which was so amazing and within two weeks my pain was
00:37:15
down significantly significantly and what I noticed was everything was starting to move in pop again so I was
00:37:21
getting Mobility back and by week two I wanted to move again so this version of
00:37:26
me that just just wanted to like go do my workout go do my work and then lay down on my back I wasn't that doing that
00:37:32
anymore and I immediately like signed back up for Pilates and I found myself dancing and hula hooping around the
00:37:38
house again and I found myself just being much more active and slowly but surely the destruction sort of fell away
00:37:46
because I had been in a pretty destructive immune process for a couple years there and it just has it's taken me I think it's been almost a year now
00:37:53
and it's just slowly but surely dropped away I also noticed a little bit of weight loss which I had gained some
00:37:58
weight over the past couple years I think it was chronic stress was doing a number on my metabolism and you know you
00:38:05
hit that 50-year old Mark and things get tough so I had some weight loss fall away I got right back down to my fight
00:38:11
and weight I'm like literally the size I was in 2019 going into all of this and
00:38:17
so I quickly started putting people on it and very similar responses uh all of
00:38:23
them had a little bit of fluff but nobody was on it for weight loss everyone had a little bit of weight fell right off got back down to a good
00:38:30
weight my mom I was particularly concerned about cuz I didn't want her to waste away again I didn't want her vomiting I didn't want her having any
00:38:35
gastrointestinal symptoms I wanted all of those to resolve it shifts your gut microbiome to a more favorable
00:38:41
microbiome if you do it right and so and we have the data on that so I was very slow and cautious with her I don't want
00:38:46
her losing any muscle mass and everybody just had these profound impacts my daughter skin cystic acne I mean a
00:38:55
decade of severe cystic acne to the point where she did not enjoy her teenage years and she was suicidal from
00:39:02
it I mean just hiding behind her hair for for years her skin I remember seeing her after 3 weeks on it and I was like
00:39:08
your skin is porcelain what happened all of her PCOS symptoms reversed um my husband didn't want to
00:39:15
drink anymore the guy is a known alcoholic he was like not interested in alcohol his blood pressure regulated out
00:39:21
I mean just all of these little things started happening and I started seeing similar effects in my patience and then
00:39:29
I at the same time I was posting about it and talking about it on my podcast and people were messaging me telling me
00:39:34
these profound stories they were like I went on it for weight loss or I went on it for metabolic dysfunction or type two
00:39:40
diabetes but here's all the other things that started happening and then people started telling me they were getting pregnant on it and you know when they
00:39:46
had been infertile and gone through rounds of IVF that were not working and just all of these Amazing Stories and so
00:39:52
of course I keep I have to research that and do more information on that and it's just been
00:39:58
I've just been unwinding I I feel like I'm unwinding a story that isn't being told so what is that story to summarize
00:40:07
what is that story that's not being told that you've come to believe these peptides are healing they are
00:40:13
anti-inflammatory and they are regenerative and they have a profound impact on our immune system in a positive way and they don't just cover
00:40:21
up and mask the insulin resistance and the metabolic dysfunction that leads to type 2 diabetes they actually heal it
00:40:29
how' you know that well interestingly as this year's gone on more and more Studies have come out and we're starting
00:40:36
to see it so many of the hypotheses I had about it are starting to show themselves in good clinical data and
00:40:42
good studies and I've seen it with my patients and I've seen it with myself so
00:40:48
I am now able to go off of it at first I could only go off of it for a short amount of time and my psoriasis would
00:40:54
come back that was the first symptoms I would start getting skin issues and I usually get it around my scalp line
00:41:00
little itches that would come back within 7 to 10 days I am now able to go
00:41:05
a month without it and absolutely no symptoms and the second I start to get brain fog or a little bit of pain I go
00:41:12
back on I cycle it like I would any other hormone I don't know if you've had any guests on talking about hormones but
00:41:17
they're done best when you cycle them because receptors get saturated and when
00:41:23
you saturate a receptor with a hormone or after a while the cell will stop listening and so you don't want to just keep
00:41:28
flooding a cell or a body with a hormone you want to take it away and let those receptors pop back up and so I think
00:41:35
done correctly and done in an elegant way that's just reasonable clinically reasonable I think that we can actually
00:41:43
start to heal some of these chronic lifestyle diseases that are so rampant and it makes me wonder if we
00:41:50
would need less and less and less of the common Pharmaceuticals that are being handed out like candy the lifelong
00:41:55
Pharmaceuticals people go on statin drugs or they go on blood pressure medications and no one says boo they're on it for life oh here's your metformin
00:42:02
for your type 2 diabetes you're on it for life I think done correctly and also the neuro regenerative process that
00:42:09
these induce in the brain they actually regenerate neurons neuroplasticity is this concept
00:42:16
where when the brain when you do something enough your brain will hard
00:42:21
wire into that and so any habit good or bad that you consistently do or any
00:42:26
thought process you consistently have if you're chronically depressed or you're chronically negative or you're you know I mean you know this you're you you're
00:42:31
self-optimizing yourself all the time and growing and trying to grow and be better you're plasticizing your brain
00:42:38
and hardwiring that circuitry so it's getting easier for you and you continue to seek knowledge these peptides offer people a
00:42:46
window of opportunity of not only giving them the onus of control back because there are some mechanisms in the brain and the dope energic Pathways that are
00:42:52
giving people the they're back in the driver's seat they're back in control of what they're doing but it's also
00:42:58
inducing this neuroplasticity so if they are to implement really positive lifestyle habits During the period of
00:43:04
time that they're on it they will hardwire that into their brain so it's like opening a window of opportunity for
00:43:10
somebody to completely change their life you mentioned some studies there that have really supported your thesis that a
00:43:17
zmek is more than just a weight loss drug and that it has these other sort of regenerative properties and these healing properties what are some of the
00:43:24
studies you've got some some things in front of you there that you brought with you what are some of these studies that highlight this in your view well so
00:43:30
there's one study in particular that I don't have the title of it written down where they looked at all of the data on
00:43:37
all of the glp1 agonists that are out there the different versions that I mentioned and they went back through all
00:43:42
of the studies and they looked at it system by system by system and I gave your team a link to that and what they
00:43:48
found is I mean going from tip to toe neuro regeneration and anti-inflammation in the brain they showed improvements in
00:43:56
card vascular tissue we just had a study come out at the end of 2023 called the select trial it was a big one yes it was
00:44:02
sponsored by Nova Nordisk who's the manufacturer of samac Tide of I should say of asmic and so people say oh don't
00:44:08
believe those studies it was a well- done study it looked at individuals in their 40s who were overweight but did
00:44:15
not have type 2 diabetes and it showed a 20% reduction in severe cardiovascular events so stroke and heart attack and
00:44:24
and others and so then people argued once that came out and said oh well that foof you know Nova nordis did it and
00:44:31
that would happen if people lost weight anyway right you you'd have improvements in cardiovascular disease well they just
00:44:36
looked at the data again and realized that those benefits were independent of weight loss whether people lost weight
00:44:42
or not they still had significant Improvement in cardiovascular outcomes which there's just nothing we don't have
00:44:48
anything out there that does that I found data showing regeneration of pancreatic tissue beta cells in type 1
00:44:55
diabetics if given early enough so if a person is type 1 diabetes is an
00:45:01
autoimmune condition where the pancreas becomes destroyed by the immune system it's different than type
00:45:07
two we don't have anything to help those people it used to be called juvenile diabetes and then type two was adults
00:45:13
onset but now kids many many children are dealing with type two so it's a big mishmash but they're very two different
00:45:19
processes they shouldn't even have the same name anyway done early U reversal
00:45:25
of that pancreatic damage to the point where people didn't need to go on insulin and were able to have pancreatic
00:45:31
healing we don't have anything that does that except stem cells they at the end
00:45:37
of 2023 they had to stop the flow trial because this was a k chronic kidney disease trial um they had to stop it
00:45:45
because the control group they needed to be able to ethically give the control group the substance because it was so
00:45:50
effective it was so effective at reversing chronic kidney disease and kidney failure that they needed to be
00:45:56
able to offer to the control group ethically and not let them continue on their journey of kidney damage so we've
00:46:03
got this mishmash of studies and then they've done little studies here and they're looking at muscle for instance
00:46:08
it's regenerative to muscle it's regenerative to Bone it's regenerative to our joints some of this is in mice
00:46:13
some of it's in humans it's regenerative to the testes and to sperm production
00:46:20
and motility when you say regenerative to say muscle when people talk about ASM
00:46:26
one of the big concerns is that you lose a lot of muscle right it's not true I mean it is true I should let me let me
00:46:33
let me rephrase that any dietary intervention or bariatric surgery that
00:46:40
induces a severe caloric restriction will lead to about 20 to 35% muscle mass
00:46:47
or I should say lean mass loss so this is a little bit of a Nuance conversation if you basically put somebody into a
00:46:54
self- starvation mode they will lose 20 to 35% of their lean mass lean mass is
00:47:01
all the soft tissue in your body so that could be your tendons and your ligaments and your brain and they they Clump it
00:47:07
all into one and they're looking at that and saying it's all muscle muscle is a percentage of that muscle isn't all of
00:47:14
your lean mass right and so that kind of makes the thing this the studies look bad there I think the other thing that
00:47:20
they don't consider in that is pathologic muscle due to metabolic dysfunction will be
00:47:27
marbled with fat what does that mean sorry well it's like a fogra when you
00:47:33
induce metabolic dysfunction in an animal which is what they do in feed lots for cows often and they do it to
00:47:38
geese to get their liver fatty you will end up with this fatty infiltrate in the muscle so the muscle goes from being
00:47:44
this lovely striad linear beautiful pattern to marbled with with fat and
00:47:52
that fatty infiltrate becomes very pathologic to the muscle and it puts the muscle itself into to an insulin
00:47:57
resistant state so once the marbling occurs in the muscle it's sort of a chicken and egg downhill situation for
00:48:04
the muscle and I do believe very strongly and I've been preaching this for decades that once that process
00:48:10
starts and it most often starts in the thighs you've probably seen the pictures of the cross-section of like this is an
00:48:15
80-year-old triathlete and his muscle looks really beautiful and linear and then here's you know the average
00:48:22
80-year-old and it's really marbled and the bone loss is significant and the fatty layer on the outside is thicker
00:48:28
but what's most important in that photo is the marbling of the muscle we don't want marbled muscle that's the beginning
00:48:34
of the end you also end up with fatty liver and you end up with fatty pancreas when you're in this metabolic
00:48:39
dysfunction State this downhill Journey that culminates in type two diabetes and
00:48:45
so one of the first things that happens when metabolic Health improves whether this is through dietary interventions
00:48:51
lifestyle strength training you name it is that fatty infiltrate starts to dissolve
00:48:57
these glp1 agonists induce that process of the fat dissolving and so I think
00:49:03
that's part of the lean mass loss that they're measuring they're just measuring it as lean mass loss but we're also
00:49:09
decreasing muscle size because we're having the fatty infiltrate start to burn itself up gp1s have also been shown
00:49:16
to peruse the muscle with angiogenesis so we get a vascular Supply so that more
00:49:22
amino acids are available to the muscle so when they looked at aging muscle in a human and they gave them gp1 Agonist
00:49:29
their muscle became healthier and less pathologic because it started to actually get better blood supply and be
00:49:34
infused with the amino acids they were eating in the form of protein so it's and then there's Pathways that are
00:49:40
impacted as well that are inducing muscle protein synthesis so gp1s
00:49:46
actually induce muscle protein synthesis they don't cause muscle wasting it's the caloric restriction that's causing the
00:49:52
wasting and they're measuring it somewhat aberant does that make sense that's that's the story I'm trying to
00:49:57
weave here yeah so but how how do how can I avoid the choric Restriction if I'm taking a gp1 Agonist like some some
00:50:04
magti or impc you don't dose it too high so you don't crush the appetite so the whole goal is to keep people at a dose
00:50:10
where they still have an appetite you don't have to crush their appetite with it the way it's being dosed traditionally is they're ramping it up
00:50:16
really fast and they're just devastating people's appetite with it and so people go from hungry and starving to I don't
00:50:23
want to eat anything and so they don't and then they often will eat less healthy version I'm sorry they'll eat
00:50:29
less volume of a poor of a poor diet so they will continue to eat junk food only
00:50:35
less of it they will continue to eat the crappy Foods they're used to eating only less of it and I've heard Johan Hari on
00:50:41
your show talk about this and he a beautiful book that he wrote his magic pill book he talks about that he found
00:50:47
himself about five or six months in and he was still just eating the same crap he was just eating less of it and what
00:50:53
needs to happen when anybody's on this at any dose is they need to be protecting their muscle with all their might they need to be strength training
00:50:59
and they need to be prioritizing their protein macros like those are the two non-negotiables I don't think doctors
00:51:04
are always talking about that and I don't think patients are compliant with that if I start micro doing though you
00:51:09
know won't I see less of the reward I see less of the cost but I would will I not also get less of the reward the the
00:51:16
positive upsides that you've described not if you're doing all the other lifestyle things so like I said it opens this window of opportunity where people
00:51:22
feel much more in control because there's impacts on the brain that allow people to be much more in control of their choices and of their thought
00:51:29
processes and of their even of their obsessions it's very interesting how it works and so people are able to make better choices and I think given that
00:51:37
window of opportunity and introducing these lifestyle interventions they're going to be much more open to it so we
00:51:42
get them exercising we get them eating better we get them doing all the things you know we get them optimizing their sleep we get them going on walks and
00:51:50
meditating and mitigating their stress all of those things are going to improve their metabolic health so it's a
00:51:56
two-pronged approach and we don't have to crank the dose we can do this slow and low and some people may need more
00:52:02
and some people may need less but the point is is the way it's being done traditionally where it's like you get your script and you walk out of your
00:52:08
office and you don't get any counseling you don't get any support this is where people are falling into I believe the
00:52:13
terrible pits of Despair so this is where the we're seeing the problems and it can be done differently where we're
00:52:19
doing a holistic comprehensive approach with a patient I was reading a 2024 study by
00:52:24
Lindsay Wang that found diabetic paent Pati taking a zc were 50% less likely to develop bowel cancer compared to those
00:52:31
on insulin what does this say and highlight about aek's role in staving of cancer
00:52:38
well that's an interesting study because insulin is prog grow so insulin is also a signaling peptide hormone very much
00:52:45
like glp1 and it is progrow when you give it to someone so someone being on
00:52:51
insulin I believe will inherently potentially make them more vul vble to cancer I don't want to say
00:52:58
certainly because I don't want to scare everybody because there's a lot of people out there on insulin but it is a progrow hormone now it's prog grow that
00:53:04
we get surges of it after we work out which is awesome we want that right we want that anabolic response but in your
00:53:11
average person who's not working out and who's not really using their insulin the way they need to they're already swimming in it due to insulin resistance
00:53:17
and now they're taking insulin because their pancreas is pooped out that's a mess that's a soup of of things we don't
00:53:23
necessarily want happening growing in the body and so that's stud looked at insulin versus gp1s it's not entirely
00:53:30
Fair because it's not a it's not a true control group but they there are other
00:53:36
data sets coming out that haven't been published yet showing really good really hopeful and positive impacts
00:53:44
on potentially reducing cancer risk and they're correlative not causitive so we can't put our finger on it and say these
00:53:50
these these reduce cancer but they looked at a you know over a million people that were typed diabetics that
00:53:57
were on somac glutide and they found a significant reduction in different types
00:54:02
of cancer that are obesity related in comparison to the folks who were not taking gp1s and those were the ovar the
00:54:09
cancers you don't want the ovarian the pancreatic the colon the types of cancers that are you know you don't come
00:54:16
back from readily and so that's very exciting it's not getting a lot of play and it's really really new information
00:54:22
so I'm excited just to watch it but it makes sense to me because these on your immune cells as well there's gp1
00:54:28
receptors throughout our entire body that's why we're getting the impacts throughout the entire body and I think that the impact that it's having on the
00:54:35
overall immunologic millu of an individual is potentially very
00:54:41
anti-cancer I mean that study that you cited there I know nothing about um asek
00:54:46
and gp1s really but in my even in my sort of you know chimp brain I go yeah
00:54:52
because if they lose weight they're less likely to get cancer right no that's totally fair and I think it's both
00:54:58
because the way that these are working mechanistically in the body and many of the studies that I've looked at are
00:55:03
showing results independent of weight loss even if they don't lose weight then their cancer risk reduces well their the
00:55:10
healing and regenerative and anti-inflammatory impacts are there regardless of weight loss or not and then you add in weight loss and you add
00:55:17
in insulin sensitivity you add in this this healing of the metabolic dysfunction and you're going to
00:55:22
significantly reduce risk for everything as well I mean that's a really good point actually CU if has has anyone done
00:55:29
a study where they give someone a zenek and even if they don't lose weight inflammation goes down well that's what
00:55:35
the select study the trial showed that that cardiovascular trial I just shared with you they just relooked at that
00:55:42
information and realize that even independent of weight because that was the big argument everyone had is well of course the cardiovascular benefits will
00:55:48
stay or will improve because they're losing weight but they found that even in those who didn't lose weight they
00:55:53
still had really good cardiovascular outcomes so yes it that's what that's what we're starting to see and so I
00:55:59
think they need to start looking at these things more readily but they weren't right they were just looking at like here's morbidly obese people and
00:56:05
here's type two diabetics and we're going to crank up the doses and we're going to see what we see but we're starting to get longitudinal data now so
00:56:12
that cancer one for instance was looking at uh patient records going way back and
00:56:18
so they had over a million you know people in there that they again it's correlative it's not positive but it's
00:56:24
showing trends it's starting to show positive Trends and so I think that's what we have to look at and we have to
00:56:29
start to flesh that out what about mental health things like depression um
00:56:35
and sort of anxiety and these kinds of things you maybe have heard that these
00:56:41
are inducing suicidal ideation and people are you know getting severely
00:56:46
depressed on them and the EU opened a whole Research into it and people are
00:56:52
very concerned about this and yet we've got studies showing really positive impacts on depression and
00:56:59
anxiety and the thing I will say about that is I'm not saying that people on OIC are not having suicidal ideation but
00:57:05
that is a little more nuanced of a conversation because number one when you lose a significant amount of weight very
00:57:12
quickly all kinds of things can go wrong you can end up with pancreatitis you can
00:57:17
end up with gall stones you can end up with severe depression uh your fat stores your hormones and so you lose
00:57:23
your hormones very quickly I've had patients who got tummy tux and came in a few months later and were losing their minds because they literally just had
00:57:29
all of their hormonal Depot sucked out of their stomach and so there's concern there that this rapid weight loss which
00:57:36
again I am not a fan of I not a fan of doing it that way but if you drop somebody's weight significantly you may
00:57:42
end up with a very depressed mood State we've also got a bit further to go with
00:57:48
that in that many people are using food as their dopamine source and as their crutch or as their coping mechanism and
00:57:54
I'm not judging I just understand that to be true you know we all have our advice and if you take that away from someone because they suddenly don't want
00:58:00
to eat because we've crushed their appetite with too high a dose then I think that we could end up with a very
00:58:06
depressed person in front of us however done correctly and what I'm seeing clinically is people are having really
00:58:12
profound benefits in their anxiety and their depression in their moods in their cognition um I'm seeing neurode
00:58:19
Divergent folks taking it who are becoming much more functional in the in
00:58:24
their everyday day-to-day I'm seeing people who are more of a Hermit who
00:58:29
don't want to go out in the world suddenly venturing out being more social so there is an impact on the brain and I
00:58:36
think it's the anti-inflammatory mechanism I think it's the dope energic system the dopamine Pathways being
00:58:41
impacted and again if we're not cranking the dose up I think that we can use these effectively to bolster mood to
00:58:49
improve cognition to improve brain Clarity and all of that leads you know an inflamed brain is a depressed brain
00:58:54
at the end of the day we have to get that point really clear depression is a brain inflammation
00:59:00
issue you've mentioned sort of sexual health a few times and fertility in passing when we're talking about as EK
00:59:06
um women's sexual health male fertility what is the the impact in your view of
00:59:13
and and is empek intervention on these kinds of things well the fertility conversation
00:59:20
is really daunting and it's kind of a long one but we are looking we are a few
00:59:26
Generations into a major fertility crisis and they say what is it by 2100
00:59:33
2,100 by 2 by 2,100 97% of countries in the world will not be reproducing at a
00:59:39
rate to repopulate themselves we are looking at a population crisis by 20 by
00:59:45
the mid 2040s they say sperm rates are going to be at zero and again that's multifactoral but
00:59:53
my firm belief at the root of this is metabolic dysfunction I I I firmly believe that metabolic dysfunction is
00:59:59
probably the biggest driver if I could press a button and fix it I would put my finger on the metabolic dysfunction
01:00:06
button and gp1s heal metabolic dysfunction and so we're seeing reversal
01:00:12
and PCOS which is probably one of the number one drivers of infertility in young women period which is really at
01:00:18
the end of the day just metabolic dysfunction it's just presenting in women with high androgens the clinical
01:00:25
picture PCOS isn't doesn't always involve um Cy on the ovaries it's just this I don't even know why it's called
01:00:30
that anymore it's a clinical picture where they have metabolic dysfunction they have high testosterone they have
01:00:36
low progesterone their estrogen gets converted readily into testosterone they end up with hair growth they end up
01:00:42
infertile it's a disaster many many young women many women in your age cohort have this condition many women in
01:00:49
your many couples in your age cohort are not able to get pregnant without IVF at this point people are not getting
01:00:56
pregnant I don't know how old are you 51 yes people in their 30s are not getting pregnant and when I ask my friends in
01:01:02
their 30s all over the world I say what's like how's how's the pregnancy going with like how how's it going with
01:01:07
your friends and they're like everybody's on IVF it's I don't know what you're hearing but it like that's
01:01:12
crazy to me that 30-year-olds are having to do IVF healthy looking 30y olds are having to do IVF so
01:01:20
we've got sperm issues and we've got egg issues it's both it's not just the female's fault it's not just the males
01:01:26
issue um we've got sperm Health we've got sperm volume we've got sperm motility issues we've got metabolic
01:01:32
dysfunction in both groups and what happens when we do have a successful
01:01:37
pregnancy is that that Offspring is being epigenetically flagged if the
01:01:43
mother is obese and dealing with metabolic dysfunction and even if the father is that fetus ends up bathed in
01:01:51
insulin in utero and they come out EP epigenetically marked for much more
01:01:56
severe risk of metabolic dysfunction and obesity in their own lives and that
01:02:01
cycle just goes into perpetuity that's where we're at we're several Generations into this as as a species and so I'm
01:02:08
worried like I'm legitimately I I joke that humans are going extinct it's not funny and it I think it's really
01:02:14
happening and I I do believe it will happen in the next few Generations if we don't write this ship and at the root of
01:02:19
it is this overarching metabolic dysfunction 2018 data out of the US that
01:02:25
was published in 2021 showed that only 6.88% of us adults are metabolically
01:02:32
healthy 6.8 so that's 93 94% of us adults are
01:02:38
cardi metabolically busted that's and that was pre-
01:02:44
lockdowns why that's a great question you know you talked about PCOS
01:02:50
and this sort of infertility crisis and then you talked about it being about metabolic dysfunction yeah where is the
01:02:56
metabolic dysfunction coming from what is the thing furthest Upstream if we were to attack it at its source yeah the
01:03:02
food supply was significantly adulterated in the past few Generations so it's starting with my parents the
01:03:08
Boomers you know they got their Convenient Food their everything was about convenience that's when we got you
01:03:14
know disposable diapers and fancy microwaves and dishwashers and all that
01:03:21
jazz well food became very convenient as well in the '90s I watched this happen in my lifetime in the '90s
01:03:27
the food supply was significantly adulterated and terrifyingly so and they
01:03:33
found the Bliss point right the perfect Emulsion of sugar fat and salt to hit
01:03:38
those neurotransmitters in the brain to make you want to come back for more
01:03:44
toxicity is a huge issue I believe toxicity in general not just environmental toxicity but it's the
01:03:50
chemicals in our food um what we're doing to ourselves so many young women today are bathing eles in toxic
01:03:57
chemicals through their beauty habits I mean the nails and the hair and the skin care and it's it's really really severe
01:04:04
so it's this sort of multifactoral thing humans are actually eating the same amount or less calories than they were
01:04:11
30 years ago it's not the caloric intake it's not that people are sloth and they're lazy and they need to do better
01:04:18
it's that we are swimming in a toxic soup we are eating a very adulterated mineral deficient protein deficient
01:04:25
chemical [ __ ] storm of a food supply and then you throw in the mass I mean to be
01:04:30
totally honest with you the massive uptick in vaccines in infants when they
01:04:36
come out I mean that's a whole different ball game than it was even when my daughter was an infant it's significantly different than when I was
01:04:41
an infant so we've just we've got a lot of things coming at these young people
01:04:47
and it culminates you know and it adds up and I think people don't realize we have a toxic bucket we all have an
01:04:53
individual toxic bucket and that bucket will become full for whatever reason maybe we've got mold exposure maybe
01:04:59
we've got too much stress it's it's multifactoral but that bucket will fill up an overflow and metabolic dysfunction
01:05:07
is a result of that and also a driver of that so it's it's very hard to put my
01:05:12
finger on why or the chicken and egg what's what's leading to what I know that there's things we can do that are
01:05:18
non-negotiable to help write the ship as best we can that have nothing to do with drugs and have nothing to do with
01:05:24
peptides and I've been talking about this for decades we must be strength training and optimizing our muscle we
01:05:30
must be walking every day like human beings do humans were made to walk and lift heavy [ __ ] right we are meant to be
01:05:37
in community we're not meant to be isolated we're meant to be around others we are meant to share our microbiomes we
01:05:43
are meant to have healthy microbiomes not these super sterilized microbiomes the abundance
01:05:48
of microbiome disruption from all the antibiotics I mean that alone causes
01:05:54
lifelong issues for people and so you stack all this up and people are sitting
01:06:00
at home they're alone loneliness is an epidemic they're eating food that comes
01:06:06
from Uber Eats or I don't know what you have here but they're ordering in they're eating processed foods for most
01:06:11
meals they're not getting out here in London I'm so happy everybody's walking but back in the US everyone just drives
01:06:17
everywhere maybe in New York they walk but any anywhere else you go you know it's like get up go from the bed to the
01:06:22
couch to the car to the desk back to the car to the couch to the bed people are
01:06:28
not exercising people are not paying attention to nutritionally dense food they're not getting sunlight they're not
01:06:34
in community I think Co really squelched Community just in so many different ways you know a lot of churches are sort of
01:06:41
disbanding communities are disbanding they shut the gyms down so there's just all of these factors that culminate into
01:06:48
a human being that isn't a healthy human being just on that point of PCOS if I was a young woman I was 31 years old
01:06:55
then I came to you with PCOS polycystic ovary syndrome and it was impacting my
01:07:01
fertility you could see I had the uh you know higher testosterone levels I had slightly hairier arms I was maybe put on
01:07:07
some weight what would you aim at what would you do I would prioritize protein
01:07:12
first of all I would go for 30 grams of protein three meals a day as best that you can I don't even care if it's
01:07:19
grassfed fancy protein I just want them eating animal protein if they will do it I want them immediately cutting out as
01:07:26
many of the chemicals that are applying to their skin and their bodies so they're not getting their hair done they're not shooting the botox they're
01:07:32
not putting the nails on they're not I mean it's just a chemical what's coming at young women is crazy when it comes to
01:07:37
their beauty routines at this point I would have them walking three times a day for 10 minutes each so three 10
01:07:44
minute walks outside preferably getting up and seeing the sunlight so we set the Circadian rhythm so it's really
01:07:50
important that you get up and outside first thing in the morning to get natural sunlight in your eyes and it's
01:07:55
really important that you see it in the afternoon as the sun is waning that sort of golden hour you know as the Sun
01:08:01
starts to wane in the sky and the sky gets golden go outside then that really helps you with sleep sleep is critical
01:08:09
cut the blue light put the you know Amber blue light blockers on at night stop staring at the phone and the TV
01:08:15
until 10 o'clock at night get that [ __ ] out of there because that is jacking up people's Rhythm which is jacking up
01:08:21
their fertility and their hormones um strength training is non-negotiable we
01:08:27
have to protect our muscle and we have to build it I'm a skinny girl and I lift more than you would believe and I don't look I can't hold it but I try so really
01:08:35
optimizing muscle that alone would be a GameChanger like if they didn't even cut
01:08:40
out I wouldn't even pull Foods away from them I would just say focus on eating getting the protein in and the other
01:08:46
foods will start to fall away and when you start to do all the other things that are good for you you start to make better choices when you feel better you
01:08:52
do better I have reversed so much PCOS in women like that next I would add in some progesterone which is available
01:08:58
over the counter but obviously do that under the care of someone who knows what they're doing so you don't take too much progesterone but progesterone's a very
01:09:03
important player in there it's actually a neuro hormone it's it's very safe and effective and I would get them eating as
01:09:11
much of a whole food diet as I could could you can you reverse PCOS yeah yeah
01:09:16
I mean they so you know genetics loads the gun and environment pulls the
01:09:21
trigger so they came out with some bad f genetic Flags but that doesn't mean that
01:09:27
that's their fate none of us it is not my fate to die a miserable death from psoriatic arthritis I will do everything
01:09:33
I can to make sure I keep that at Bay and that's something that medical doctors don't tell you you go in they
01:09:39
say you have this there's nothing we can do and I'm like could I take a multivitamin could
01:09:46
my is changing my diet going to do anything and back when I was growing up there was like there's nothing you can do good luck at least now doctors are
01:09:53
starting to get a little more Savvy and realizing it's more nuanced and I'm I'm starting to see the professions come
01:09:58
together more and realize like Diet actually matters and I'm starting to see it in the headlines of the medical journals like Diet actually matters
01:10:03
lifestyle matters light matters you know but all of these things what what I tell patients is I'm not going to cure you
01:10:11
you are genetically and epigenetically primed but we're going to try to keep that as quiet as possible we're going to
01:10:17
try to keep you optimized so that this over here doesn't rear its ugly head but you know throw in a bad viral infection
01:10:24
or throw in a big stress or throw in you know something major like a birth child
01:10:29
birth and you might get off kilter again but that doesn't mean you don't have all the control in the world to help
01:10:35
mitigate that I have to say you know as someone that comes from I'm going to try and pronounce it again naturopathic
01:10:41
medicine it is quite surprising to hear you talk about micro doing on a zenek I
01:10:48
know because you know I think naturopathic medicine you'd imagine they were very much against micro doing or
01:10:54
dosing any sort of chemical pharmaceutical right so how do you square the circle there because it's a
01:11:00
peptide and it's been appropriated by the pharmaceutical industry because of its delivery system but there's many
01:11:06
other peptides that are available over the counter for instance in supplement form like bpc157 which is a regenerative
01:11:13
peptide it's also anti-inflammatory all of these peptides generally are regenerative anti-inflammatory and
01:11:18
healing they all just kind of have their special skill set so we've got a variety of different peptides that were pulled
01:11:25
by the FDA because they work is my opinion but we also have ones that are available over the counter that are in
01:11:30
sprays that are in pills if you go get hurt you can order them online it's legal I'm not talking any black market
01:11:36
this these are reputable companies in a supplement form and you can induce phenomenal healing in your body these
01:11:42
are available people just don't know about them and they don't know how to use them and they are a bit expensive this is just another peptide it just
01:11:48
happens to be held over here and it's being used in a way by brand name
01:11:53
pharmaceutical big Pharma compy companies in a way that I just don't think is appropriate for peptide use
01:11:59
you've used that phrase done correctly a few times when you're talking about the micro doing of a zenek and you've also
01:12:06
highlighted there but also previously in this conversation that people are using it wrong so I or using it in too high of
01:12:13
a dose so I amum I brought with me today some little science lab which I've got over there in the corner because I would
01:12:19
like you to show me when we talk about micro doing a what micro doing is as a term what does that mean but also could
01:12:26
you show me the comparative difference in how you would and you are giving your patients a zc what dose you're giving
01:12:33
them out comparatively yes to how it's typically being administered in what dosage um for the sort of weight loss
01:12:39
effects that we've talked about and that most people know it for sure yeah absolutely so let me bring over the
01:12:46
zmek okay so this is what they start people on and then every month every
01:12:52
four weeks in the traditional model with the brand names like OIC and wovi
01:12:58
and mro they double this is this would be specifically for stide okay so let me
01:13:04
back up here just I've got my um some with you so typically when they administer a zek and stide they do it in
01:13:11
a pen which you kind of self inject which is at a controlled dose yes so you
01:13:16
can't give yourself whatever uh quantity you like it's kind of like a set dose
01:13:22
you go and it injects into you yep okay okay so they start them here with that
01:13:27
much in it so for people that are can't see cuz they're listening on audio it's 0.25 milligrams okay and then every
01:13:35
month they double the dose about over 16 weeks they double the dose until they
01:13:41
get folks generally now smart docks will stop people where they need to stop but
01:13:47
the standard is to get them up to about here per week per month I'm sorry per
01:13:54
week yes per week they do this per week they get them up to here this is what the studies have been done on and so
01:14:01
this is how it's traditionally dosed and if you're severely diabetic or obese I could see the rationale I'm arguing I
01:14:09
still don't think that's necessary when you have the appropriate lifestyle interventions okay if you're treating someone comprehensively using other
01:14:16
peptides using hormones getting people to do the healthy lifestyle changes I don't think this is necessary and I
01:14:23
think this leads to very high risk for side effects so we went from was it 0.25
01:14:29
to 2.5 basically so 10 times more yeah over the space of x amount of weeks 16
01:14:35
weeks 16 weeks okay so they 10x the dosage over 16 weeks yep um which looks
01:14:40
like what is a lot so you're taking that much injected into self injected every
01:14:46
week every week okay and you do that you're theoretically supposed to be on that dosage forever yes and they don't
01:14:52
ever stop they don't take breaks they're not concerned about receptor sensitivity it's just they just go it's just you're
01:14:59
on this and you're on it for life now some there are really good weight loss docs out there and they are helping their patients get off of them and
01:15:04
actually the more recent data is showing that when folks are exercising just it doesn't even matter what kind of
01:15:10
exercise when folks are exercising in addition to they can come off more successfully and maintain the weight
01:15:15
loss so that's promising however my argument is in somebody who's metabolically optimized now this isn't
01:15:22
everyone this isn't your severely obese patient but in somebody who's metabolically optimized I give them a fraction of this
01:15:29
and that differs by person but I actually have to use an insulin syringe so that I can do a fraction of the
01:15:35
starting dose and I may never elevate it I may never ramp it up so compared to
01:15:40
the 2.5 milligrams in there you're giving out how much I'm giving a fraction of
01:15:46
0.25 I'm giving a fraction of this so you might be giving 0 Z it depends it
01:15:53
depends on the patient and without getting into detail because whenever I do people start playing with their
01:15:59
dosage themselves and I've heard seen crazy things in the comment section of my posts on Instagram so I don't want to
01:16:05
tell people exactly how to dose um but it depends it depends on what they're going and this is a bigger conversation
01:16:10
because I don't ever do seacu tide as a monotherapy I never do it by itself I
01:16:15
never just crank people on seacu tide and hope for the best if that is the only Geo if I'm sorry if that's the only
01:16:22
peptide they're using they likely will have to keep going up and so I have one patient who is obese and has some weight
01:16:29
to lose and I have taken n months to get him to here which is roughly one one
01:16:36
milligram that's one milligram so he's on one milligram and I really don't want to raise it I really want him doing more
01:16:43
of the lifestyle interventions to start to heal the metabolism as well so it's a multipronged approach I'm trying to heal
01:16:48
the metabolism at the end of the day this is one tool but there are other tools but this is a pretty potent tool
01:16:55
so in the case of someone that is micro doing how frequently are they taking
01:17:00
that small dose in the small sort of Petri Edition front of you it depends so give me give me a case study of the
01:17:06
typical person well it depends on what I'm going for what my short-term goals are what my long-term goals are so for
01:17:13
myself I was having to do a fraction of this droplet here not this this once a
01:17:20
week as people heal and improve they're able to space that out some people can space it out two weeks
01:17:27
so some people are dosing every two weeks some people are dosing once a month it really depends some people are
01:17:32
there's a lot of folks thinking they're micro doing but they're actually just barely going below that 0.25 they're still almost right at it so they're
01:17:38
still doing a large percentage of this and that's not really micro doing but they're getting results and so my goal
01:17:43
is always just to dose people just below symptoms I never want them symptomatic I
01:17:49
never want them saying I'm nauseous or I'm throwing up or having any of that there's no need for any of that I want them just below symptoms and I want them
01:17:55
continually improving and getting the results I'm looking for that might be lowering of blood pressure it might be
01:18:02
Improvement in mood it might be you know continuing clearing of their skin lesions it depends on what we're going
01:18:08
for and then my goal is to cycle this so I will try to get them off for as long
01:18:13
as I can and I will try to try to take breaks for as long as I can because I want the cells to resensitize so that
01:18:18
might be like I said two weeks it might be a month some folks might just do this a couple times a year they may not be on
01:18:25
it continuously they might just do what we call a cycle this is you might be familiar with this um if you've
01:18:30
interviewed anyone on testosterone therapy often it's a cycle and so they'll do a few months maybe 90 days on
01:18:36
and then they'll take some time off it totally depends on the patient and what I'm going for though and it depends on
01:18:41
again what am I trying to accomplish shortterm and what am I trying to accomplish long-term and how compliant are they being with the rest of the
01:18:47
treatment plan so give me a case study then of someone who has micro doed with you successfully and they've gone from
01:18:54
ill health and some form to healthy so my mom is a great example she started on
01:19:00
a tiny little bit cuz I said she's older and she's a bit frail and she was going into it with gut issues already so a
01:19:07
very tiny little bit she actually ramped herself up I'm not sure why she ramped herself up a bit she got a bit
01:19:13
symptomatic so she was still at well below this droplet amount and I've
01:19:19
recently it's been maybe nine months I've recently brought her back down to a droplet and I'm trying to keep her there
01:19:26
and she's still doing it once a week and we're starting to play with how long can she go off of it before we start to see
01:19:31
symptoms I don't want the symptoms to come back full bore because then we know tissue destruction is happening I'm
01:19:37
trying to heal people in the process of treating people if that makes sense I want both to happen but she also needs
01:19:43
to be compliant with all the things and so something I'm hearing about a lot which is a great case example is many of
01:19:48
my colleagues who I have a program where I teach people how to do this and many of my colleagues are thinking their
01:19:54
micro do and they're not and then they start calling me and they're like they're either running into symptoms or
01:19:59
they're hitting a wall and their patients are plateauing they say it's not working anymore I'm like well what are you going for if they're going for
01:20:05
weight loss they are going to Plateau if they're not because they haven't implemented the strength training yet or they haven't implemented maybe some of
01:20:11
the other bioidentical hormone replacement or whatever it may be you know they're not doing the they're not
01:20:16
taking care of all of it holistically and so they're running into some barriers what is what is the role it's
01:20:23
playing if if you're doing it at such low doses what is the role that it would play for someone with for example
01:20:28
chronic pain or some form of inflammation in their body why is such a small dose IM important in the bigger
01:20:35
picture you described there of getting their health back in shape is it because of you said earlier about the brain fog
01:20:41
and getting them to a state where they can make better decisions or I think it's actually also in the brain so glp1
01:20:46
is secreted in the brain something that most people think is that it's secreted in the gut and then it makes its way to
01:20:52
the brain there's actually different Reg of the brain where glp1 is produced and there's receptors all over the brain to
01:20:59
receive the glp1 so I think something very important is happening in the brain that we really are only just starting to
01:21:05
understand and I believe that the downstream impacts of that of healing
01:21:11
that like I said at the beginning if we heal the brain we heal the immune system we heal everything Downstream and so I'm
01:21:18
really trying to have a cognitive impact and so that's it becomes more critical than to
01:21:24
do all the lifestyle interventions that reduce neuroinflammation we want to make sure they're taking supplements that are
01:21:29
supportive for brain health we want to make sure that their lifestyle habits are supportive to brain health they're
01:21:34
not continuing to drink a bunch of alcohol although this makes most people not want to drink even at tiny doses
01:21:39
most people just want to stop drinking it's really phenomenal they want to kind of stop doing all their bad habits they want to stop chronically shopping they
01:21:46
want to stop all the dopamine chasing habits that they have which is is now if you go too high though you start to
01:21:53
impact reward systems and I can see where they start to get depressed so I'm trying to have a positive healing
01:22:00
regenerative impact on the brain and the immune system to ultimately heal them up and hopefully I can take them off of
01:22:06
them or maybe they might have to revisit it if there's a flare if something comes up in their life that sort of set like I said you kind of get set back over the
01:22:12
edge we might have to bring it on board for a minute but I'm ultimately doing an initial healing phase and then I'm doing
01:22:19
a maintenance phase you mentioned alcoholism there and you mentioned your husband earlier as well how is there
01:22:28
research to show the impact that it has on addictions they're studying it but people want to stop smoking people want
01:22:34
to stop doing cocaine people want to stop doing all kinds of things and it's very interesting and they Johan actually
01:22:42
talks about this in his book and he he does a nice job of breaking down the science there on it they looked at rats
01:22:48
and they thought okay well if this is just crushing the reward system then it would crush all the reward systems but
01:22:54
it's not crushing libido for people and it's not crushing some of the other reward seeking behaviors it just seems
01:23:01
to be crushing many of the ones that are pathologic or not so great for our health in the long run and he actually
01:23:08
talks about a study that I've read as well where they took rats and they gave them sort of that like yummy Emulsion of
01:23:14
that sweet sugar salty deliciousness and then they gave them rat chow and when they put them on seacu tide they stopped
01:23:21
seeking out the yummy devast I mean that's that Emulsion is what makes you become very metabolically you know
01:23:29
compromised and they still ate the rat Chow they still went for they went for the healthy food I don't know how
01:23:34
healthy rat Chow is that's debatable but they went for the more nutritionally dense food and they actually stopped
01:23:40
seeking out the pleasure food and I I'm seeing that across the board with all kinds of behaviors I got a message from a lady she said I had no idea I had such
01:23:47
a severe online shopping habit like I would just fill the cart up and purchase
01:23:52
and then she started filling the cart up and not purchasing and now she's not even online shopping she's not even like going in to make the to have the
01:23:59
experience it's really interesting what's going on in the brain there in your opinion it plays on the
01:24:04
hypothalamic pituitary axis to some degree and it is impacting dope energic Pathways and at the end of the day the
01:24:10
dop anergic Pathways our dopamine seeking system is in a simplistic way to describe it is
01:24:18
our addiction system so we chase that dopamine dragon that dopamine Dragon might be sex it might be gambling it
01:24:25
might be cigarettes it might be whatever it is whatever that thing is that gives us that hit and interestingly about
01:24:30
dopamine and why it BEC such a process I mean I think a lot of it is these cell phones it's this quick we've got a very
01:24:37
quick reward system Society you know back when I was a kid we had to like wait outside in the freezing cold all
01:24:42
night to buy concert tickets and now you guys are like well I'm just going to buy whatever I can afford to get the best seat it's a very different world you
01:24:48
know and everything's right at our fingertips and it's very it's very quick response and so our dopamine Tre is
01:24:54
really screwed up dopamine is healthiest and signaling best when we're seeking out the
01:25:01
challenge it's not when we get to the it's not when we win have you ever wanted something really badly and then
01:25:07
you succeeded and you got there and you were like I'm just not feeling it just wasn't what I it's because it was the
01:25:14
journey there it was the conquest of getting the thing of achieving the goal that's what gave you the dopamine it's
01:25:20
not as much getting the thing at the end of the day and this is playing somewhere in that system system and people are
01:25:25
just not having the reward seeking Behavior as they were I had so many people reach out to me and say when it
01:25:32
came to food in particular this must be what normal people's brains feel like I
01:25:37
don't wake up obsessed thinking about food I don't go throughout my day obsessed thinking about food I can actually think about other things really
01:25:43
what we're saying here then is that hunger is much more than a desire for food hunger is a much
01:25:52
broader sort of psychological phenomenon that's about dopamine and reward and all these things so when we attack so g1's role isn't
01:26:00
just in hunger it's in this bigger psychological sort of incentive structure it was weird because as you
01:26:06
saying that this morning I didn't eat right because I didn't have breakfast and I didn't have lunch because I was doing my annual health check so they say
01:26:12
you got to fast beforehand so I didn't have anything and my first meal per se was at about 2: p.m. you can see my
01:26:18
little jab in my arm from they got you the little canula thing they put in my arm um and I got to about 3 p.m. and I
01:26:25
hadn't eaten and I have this drawer in my car the car we typically pick up
01:26:30
guest in and it's got some like less healthy snacks in I try and stay out of it but because I hadn't eaten for some
01:26:36
reason I was like I need to go in the drawer and eat food I need to go and eat the sugary stuff so as you were talking I was thinking is the administration of
01:26:43
jp1 and zeg just bringing down that noise a little bit to the point that I
01:26:48
no longer want the sugary snack drawer because I was thinking to myself this morning if I if that was the start of
01:26:56
the day when I was less hungry I wouldn't have been thinking about that snack draw but because the day went on
01:27:02
and I became more hungrier I had a greater pull on dopamine so there's people living typ you know their
01:27:08
everyday lives with this kind of Greater demand for dopamine for whatever reason and it's coming from gambling or porn
01:27:14
addiction or or shopping addiction and what gp1 is doing is it's just bringing not just the the I need food that the
01:27:21
hunger down it's bringing the sort of dopamine pathway down in terms of volume it's quieting the noise that's a really
01:27:27
good way to put it and that's how people describe it is they call it the you know the the the food noise or the hedonic
01:27:33
urges it it quiets the noise down and that's why I was saying earlier that it gives people this wonderful window of
01:27:39
opportunity to be back in the driver's seat they sometimes for the first time in their life have full control over
01:27:45
what they're choosing to eat when they're choosing to eat what they're putting in their mouth and some people didn't have that control before and it's
01:27:52
not just dopamine we've got leptin we've got gin we've got these different appetite they're also peptid signaling
01:27:58
hormones and they all play together and they don't play well if glp 1's not in
01:28:03
there so if leptin is happening and gin is happening and we can go into the
01:28:08
details of that if you want if g1's not there the orchestra doesn't work and there's a lot of folks sitting around
01:28:15
with leptin resistance insulin resistance they're not responding to Gin this even the cell receptors getting to
01:28:21
the edge of the membrane is sometimes gp1 contingent and so my argument is that
01:28:28
sometimes the tiniest little amount might be what that person needs to kind of harmonize the
01:28:34
orchestra maybe you know we can't have and this is the other reason I don't love it in monotherapy Imagine a jazz
01:28:40
band and you just had one big bass drum that would be ridiculous it would sound terrible right like the Nuance in the
01:28:45
Jazz drummer is what makes Jazz so cool a lot of folks are using this at this
01:28:50
dose right this huge dose and that's the big old bass drum and they're just
01:28:56
crushing the whole brain circuitry to suppress hunger period and they're
01:29:02
ending up with all these Downstream side effects which are not fun my argument is if we just harmonize the orchestra but
01:29:09
sometimes we need a little estrogen or a little progesterone or we need a little bit of this or that we need to do some lifestyle things to get the leptin
01:29:15
resistance to reset and the insulin resistance to reset but we might need a little bit of gp1 on
01:29:21
board every single time you eat you have an opportunity to improve your health
01:29:26
and that's why I love Zoe because Zoe helps me to make the smartest food choices for me and my body and as you
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01:29:50
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01:29:56
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01:30:03
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01:30:09
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the code ce10 checkout what if someone says that we haven't got clinical studies yet to
01:30:22
prove that micro doing is safe over the long term and it could be doing long-term damage because these you know
01:30:28
compounds have only been around for what a couple of years now and in terms of people really using them on
01:30:34
mass well I think we would be far more concerned with high doses and that's
01:30:39
what most people are on are on high doses and we're really not seeing the safety signal blowing off the way that
01:30:44
people are concerned about in fact we're seeing the opposite of that some really good data has come out refuting many of
01:30:51
the studies that were so concerning in the past few months and some of it's just being presented at different
01:30:57
conferences so it's not being published yet but I keep up with all of it and it's very exciting we're not seeing a
01:31:03
signal on pancreatitis we're not seeing bowel obstruction um gastro pris I think
01:31:08
it's fair to say that the highest risk group for gastroparesis is type two diabetics it's because they are sugaring
01:31:16
up their Vagas nerve the high blood sugar is actually destroying the Vegas nerve which is causing low-grade
01:31:21
gastroparesis so they're already sitting on the edge of of it in many cases and then they're being cranked into these crazy high doses and getting thrown over
01:31:28
the edge a real concern is bilary disease so gall stones when you go on a
01:31:34
very severely calorically restricted diet your bile sledges up in your gallbladder so a gallbladder is already
01:31:42
very often compromised in an obese individual and it's already sludgy and it maybe already has some Stones forming
01:31:47
and then they go on a caloric restriction that lack of food going through the digestive tract will cause
01:31:53
the bile to sludge up they'll throw a stone into the pancreas the number one cause
01:31:59
of pancreatitis is fatty pancreas which people with metabolic dysfunction already have the N the second cause is a
01:32:06
gall stone and the third cause really is excessive severe weight loss done too
01:32:12
quickly so we're taking people and thrusting them up on these high doses they're often already sitting on the
01:32:18
edge of many of these conditions and then they're getting thrown over the edge it's like well yeah no wonder when I started looking at the terrible side
01:32:25
effects I was like well of course I mean anybody who is severely diabetic or severely obese is already sitting on the
01:32:31
edge of that and so my argument is why are we throwing people on these high doses and sending them over the edge I
01:32:37
don't think taking a tiny amount of something is nearly as concerning as the high doses but the rates that you're
01:32:45
hearing in the media are not the rates that are showing up in the studies even of these terrible side effects I just mentioned I have always believed that
01:32:52
there's no such thing as a free lunch that's SP in life and you know whenever someone tells me that something is good
01:32:59
for me um it always comes with a cost you know
01:33:04
like that just seems to be the way that life works and I like that life has that balance to it where there is no you know
01:33:10
anything that's worthwhile whether it's starting a business having a great marriage or relationship raising kids
01:33:16
right there's so much of an upside and there's so much of a cost you know and so as it relates to micro doing of zek
01:33:22
my brain is going there's got to be a cost if there is any reward there has got to be a cost that's
01:33:28
fair well you have to think about the risk reward ratio and that's something that we don't talk about in medicine I
01:33:34
think Co really showed that you know you have the risk of covid the real risk of
01:33:41
covid whatever that looked like depending on the scale of uh susceptibility you had for poor outcomes
01:33:46
so if you were 65 or older you were in poor health there was a real risk and
01:33:51
then you have the reward uh we have to look at what lockdowns did we have to I mean 146% increase risk of suicidal
01:34:00
ideation all kinds of I mean I the stats on that I don't even want that like makes me sick when I start thinking about what happened um I was just
01:34:06
driving over here and the Uber driver was telling me how nobody goes to church anymore and all the bars are the pubs are closing because the culture the pub
01:34:12
culture is going away not because of drinking but because of just people join gathering in community you know like he
01:34:18
said it was Co was the end of so much of London that he saw and he's been driving for in some form or another for 15 years
01:34:25
through London and so we have to look at risk reward ratio and the risk of
01:34:31
walking around in a chronically inflamed state for somebody who say has ptic arthritis I have thought about this and
01:34:36
I'm like you know what the risk that I'm seeing in the data from high doses of this is probably not nearly the risk of
01:34:44
a tiny dose of it and it certainly is better than the clinical outcomes of walking around with raging psoriatic
01:34:50
arthritis for the next 30 40 years which is dementia my spine fusing lack of
01:34:57
movement muscle wasting chronic pain so on and so forth the real risk of
01:35:05
obesity is tremendous and something that a lot of
01:35:10
people don't appreciate is when we start to gain weight in middle age that's a lowgrade insulin resistance happening
01:35:16
and so a woman will gain you know somewhere between 45 and 50 she might gain 10 pounds okay we get a little
01:35:21
thicker as we get a little older okay maybe the next five years she gains another 10 pounds and we just sort of
01:35:27
accept it as a society like all our moms kind of get bigger right and all moms just get bigger and they all end up
01:35:32
looking like they you know the whole the moms the grandmas everyone ends up in my family round by the end of it well now
01:35:39
my family starting to drop dead of heart attacks they're all on lifestyle medications they're all on statins and
01:35:46
blood pressure medications and all of these things and my thinking is what if that process never even started what if
01:35:51
I was able to intervene with not just glp ones but all the other tools I had available to me that I didn't have when
01:35:57
they started I wasn't out of school yet I didn't know what I know now what if I was able to intervene and give them
01:36:02
decades more of a high quality life and that's what longevity medicine is that's what hormones are that's what
01:36:08
bioidentical hormone replacement is and what these other peptides are that we've been using for a long time in clinical
01:36:14
decades in clinical practice and I don't know if you you probably don't but the
01:36:19
um Women's Health Initiative 20 plus years ago came out with data showing
01:36:25
estrogen and progesterone replacement therapy is dangerous and all women were immediately ceased doctors got scared
01:36:32
everybody got taken off their hormones we just destroyed an entire generation of women over the past 20 years doctors
01:36:39
that were smart like myself and my colleagues we read the data and we realized that they were giving them
01:36:44
progestin and not progesterone and there was nothing unsafe about what they were getting and so we kept everybody on
01:36:50
their hormones and I'm like well here's informed consent would tell the patients this is the data this is what we're
01:36:55
going to do they agreed or didn't agree that's called informed consent here's your risk reward ratio and they've just
01:37:02
reanalyzed the data in the past few months and decided that they were wrong it was bad data they shouldn't have
01:37:07
taken all these women off of hormones the amount of dementia and cardiac disease and bone fractures and on and on
01:37:15
and on that happened because those women were starved of hormones is devastating to me so it comes down to
01:37:24
understanding the mechanism of action of how these things work sharing that as best as you can with your patients and
01:37:30
then having a conversation and letting the patient decide so but in the case of the micro doing you're going to tell me the upsides in that informed consent
01:37:37
scenario what would you tell me the downsides might be I would tell you the downsides that we see in the data with
01:37:42
the high doses okay but and you would extrapolate from there that you would
01:37:47
have those downsides meant but in smaller frequency much much smaller po
01:37:53
but also you keep a sharp eye on your patient you don't just send somebody out with a prescription and say see ya good
01:38:00
luck you know it's close monitoring you're making sure to keep track of things we're running Labs we're checking
01:38:05
in we're making sure symptom pictures aren't showing up and it's upside versus
01:38:10
downside people are going to listen to this and they're going to think okay so I should be micro doing as
01:38:17
zc and what might happen is people will go online and they'll try and buy zenek
01:38:22
and then they'll at home start I don't know putting it in that tea or whatever oh no that's not a good idea I would I
01:38:29
don't know what the situation is in the UK but I know in the United States we have longevity doctors we have Smart functional medicine doctors we have
01:38:35
doctors that have access to compounding pharmacies and I'm hearing at least in certain parts of Canada there are
01:38:41
compounding pharmacies I don't know what the situation is in the UK I believe
01:38:46
there are compounding pharmacies are being driven out by big Pharma because they're pretty punk rock they're doing
01:38:52
individualized medicine for patients they create medications for a patient at the dose that's tolerable for the patient and I highly encourage folks to
01:39:01
do their research and find a doctor who's willing to work with them and at the very least consider the starting
01:39:07
dose that is in the pre-filled pens and talk to your doctor about not escalating so quickly and making sure that you
01:39:15
implement the other lifestyle factors aggressively so that you don't have to increase the dosage and I'm hearing from
01:39:22
people in my program that are doing quite well that way they don't have access to compounding pharmacist they don't even have access to like a longevity doctor I understand that's not
01:39:28
available for everyone and there's there's economic issues I get all that so they're finding great success in that
01:39:35
0.25 milligram and they're being really diligent about all the other lifestyle interventions and they're doing awesome
01:39:41
and so I don't know any doctor that would want to crank up a dose of any medication if a patient came to me and
01:39:47
said doc I want to start on this you know the standard is this dose I want to start on this dose and I don't want to
01:39:52
go up I'd be like Hallelujah cuz anytime you increase the dose of anything you're going to get side effects are you seeing
01:39:57
the weight loss benefits in people that are micro doing if they're metabolically optimized and or they really start
01:40:04
working on it so if somebody walks in and they've got 30 40 pounds to lose I
01:40:09
have seen them successfully micro doing so long as they take that opportunity to do all the things they cannot sit on
01:40:16
their ass and eat junk food all the things what are all the things so strength training a couple times a week
01:40:22
lifting something heavy that might just mean filling up water jugs and picking them up and walking across your room it might mean picking up your cat and doing
01:40:28
some squats every night just starting to use the muscle and why strength training because muscle is the currency of
01:40:36
metabolic Health like we need muscle mass in order for our cells to be
01:40:41
optimally insulin sensitive it's just how it works we gobble up our blood sugar and we regenerate our mitochondria
01:40:49
predominantly in the muscle so we need muscle it's a very important organ system it's not just a moover you know
01:40:54
we don't just move our our bones around with it you've got to have go Dr Gabriel Lion on and she'll give you the whole
01:41:00
muscle the conversation but muscle is absolutely non-negotiable and so
01:41:05
strength training man woman I don't care what age they are it's something we have to focus on it might be push-ups it
01:41:11
might be I saw some cool stuff around the parks around here you guys have you it's way better here than it is in the
01:41:17
US it's like not even emphasized so my husband's like that's like a situp thing and that you know it was like some
01:41:23
blocks of wood with some metal on it but it was set up as a little exercise area in one of the parks so making sure
01:41:28
that's dialed in prioritizing protein okay making sure the food you
01:41:34
choose to put in your mouth is nutritionally dense what's the bang for your buck is it brightly colored is
01:41:42
it coming from a lab or coming from a factory in a package with a hundred
01:41:47
ingredients in it or is it a whole food right is it is it food that came off the farm is it food that looks like how God
01:41:53
made it however you want to think of it simplistic so I'm G to start lifting weights I'm going to
01:41:59
um yeah I'm G to start lifting weights and then I'm going to start eating lots of protein yes and what else do I need
01:42:04
to do make sure that you eat a variety of colorful Foods right so just just focus there I hate taking Foods away
01:42:10
from people start there you'll fill up and then you don't need the rest right you're going to get up and go for three walks a day like I mentioned three
01:42:17
10-minute walks and I think ideally morning because you're getting your morning sunlight go out at noon so your
01:42:23
High Noon light you're going to do wonderful things for your leptin and for your circadian rhythm if you hit the light at three times a day and then
01:42:29
you're going to go for that late afternoon walk so that might just be going out with your dog it might be going out with a friend whatever might
01:42:34
be going out at lunch break whatever just go around the block these are are these these sound very similar to your
01:42:40
six pillars for a pain-free life which you write about in your book painfree and strong yeah so we covered a few of
01:42:46
them here we've covered the strength training one and I had some really awesome stats that I found um in one study 186 people with type 2 diabetes
01:42:54
were split into three training programs one was one group was strength training the next was moderate cardio training
01:43:00
and the third is a combination of both and the strength training only group lost the most fat gained the most strength and lean body mass and had the
01:43:07
biggest decrease in insulin resistance and that was in women's health and you know I think one of the things that
01:43:13
we've always assumed and I've certainly assumed it is that as I get older I'm just going to lose muscle and that's just what it is yeah it's not true no
01:43:20
it's we even have studies showing that folks in their 70s can maintain and build muscle even if we maintain it
01:43:26
right even if we can just maintain it so it's critical this is not negotiable I have a 24y old daughter who is starting
01:43:33
to understand this she's starting to get it right and she's like okay mom what do I do and I'm like just pick up your dog
01:43:39
she's got two different dogs that are two different sizes I'm like just do squats with your dogs start doing push-ups off the side of your couch you
01:43:45
can do this at home right there's so many opportunities online now everything's out there and it's free you just have to actually put in the time
01:43:52
we've covered movement there we've covered strength we've covered the food and gut the four others you've got in this pillar one of them is um sleep
01:43:59
sleep so sleep can be elusive for folks especially if they've got hormonal issues and or they've got insulin
01:44:06
resistance and metabolic dysfunction which drives the hormonal issues so it's really important that
01:44:11
you you have to prioritize your sleep but you have to protect your sleep and when I say Protect it I mean are you
01:44:17
sleeping with a husband who's snoring all night long are you in a really noisy environment do you have to add ear plugs
01:44:23
in is it too bright in your room do you have to put an eye mask on like what's basic sleep hygiene get the TV out of
01:44:28
the room the TV is not helping you the bedroom is for sex and sleep get the husband out of the room
01:44:36
maybe well you know what people snore when they're metabolically unsound and they're overweight too so if we can get
01:44:41
the husband involved in the activities then hopefully everybody gets better and the snoring goes down so yes you'll get
01:44:46
a new husband I guess well yeah when I was dating it was a big deal actually I was like I would ask them on the first
01:44:51
date how's your sleep and if they they said it was not good I'm like that's not agreeable to me I'm not messing with
01:44:57
this so just really opt going to bed at the same like be an adult be a grown-up we put our kids to bed at a normal time
01:45:03
every day we have a rhythm with them right they go to bed they get up the same time every day we have to do that with adults stop sleeping with your
01:45:08
phone by your head stop sleeping with it in the room what about sleeping pills I don't love sleeping pills I have used
01:45:15
them clinically I don't love ambian or any of those types of drugs but there are other options to help people get to sleep we can use herbs I think pretty
01:45:21
well too but we have got to we've got to do what we've got to do to reset the sleep but I'll tell you number one if
01:45:28
your sleep is off and you're not exercising every day I don't even want to hear about it because if you're not
01:45:33
exhausting your energy like you would your puppy or your child of course you're not going to be able to sleep and
01:45:39
number two if your circadian rhythm is screwed up if you're not getting out that morning sunlight is so huge if
01:45:44
you're not getting out in the daylight I know when it's gray in Oregon sometimes it's gray all day long and I can't even tell what time of day it is and I will
01:45:50
still go out there in a rain coat and make sure I'm out in the daylight even though it's gray as heck so that is
01:45:56
absolutely critical both of those things will help improve your sleep why did you include mind set as one of your six
01:46:03
because you have to believe that you're going to accomplish this that goes into the dopamine pathway it's a challenge
01:46:08
right this is my challenge this is and and I mean Challenge in a good way I think of it as a quest not as a negative
01:46:14
challenge right I don't want people to ever feel like they're up against an insurmountable wall I I heard that a lot
01:46:20
with covid when I was talking about weight loss and metabolic optimization people would say I have tooo much weight to lose there's no point there's always
01:46:27
a point we can always start to decrease inflammation and improve metabolic Health even if the scale isn't shifting it doesn't matter so we really have to
01:46:34
go into this with a Winner's mindset we have to be goal oriented I'm
01:46:39
sure you could actually chime in on that too like what are the things that you do that drive you to get up and go do the things that you do that might be hard or
01:46:46
challenging but you know they are what you need to do to move the needle and that's mindset it has to start there if
01:46:52
it doesn't start there if you don't make a decision a concerted decision to execute you're never going to get there
01:46:58
that's super difficult isn't it it is cuz people are so riddled with their own traumas and their own complex
01:47:03
psychological state that getting them to shift their perspective on the world is is like trying to convert a religious person to another faith it is but I
01:47:10
think people are outcome oriented and I I see the potential but that's where I said remember short-term long-term goals
01:47:17
if I'm only focused on the outcome I'm never going to get there and when I do that dopamine's going to drop off and I'm going to be like [ __ ] I'm going to
01:47:23
fly you know just fly back to where I was it's the short term it's the I want
01:47:28
to win I want to feel better I want a better life for myself I want a better life for my children I want to I want to
01:47:34
be a better person for the people around me maybe people are single and they're looking for someone I always get asked that how' you find a great guy I'm like
01:47:40
you have to be a great person you have to make yourself a great healthy person to attract another great healthy person so it's the journey it's not the
01:47:47
destination right that's just Health 101 it's the journey not the destination interestingly in your um in your book
01:47:53
you don't have a chapter about this but you've said in other situations that
01:47:59
saas have been a pretty critical uh beneficial tool for you in your health over the past couple of years yeah son
01:48:05
just getting hot like you can get hot in a bathtub you can get hot through exercise but just getting your body heat
01:48:12
up will induce heat shock proteins which does so many great things for your brain and immediately makes people feel better
01:48:19
people wonder often they go do some aerobic exercise and they think it might be the endorphins from the run and I'm
01:48:25
like if you turned into a sweaty mess during that you got a whole bunch of other benefits too right we moving lymph we're removing blood it doesn't sound
01:48:31
that sexy but those heat shock proteins are it they have a significantly positive impact on our immune system
01:48:38
somewhere around 40% reduction in pneumonia when induced so like do all the things right just go get hot and
01:48:44
when I am out of sorts and my immune system's flaring and I'm sort of at the end of my wits and I don't know what to
01:48:50
do I just think I got to go cook the sh out of myself I just got to go get hot and get
01:48:56
sweaty and then generally the solution comes to me or I have a better path
01:49:01
ahead of me right that a little bit of light will come out ahead I'm like okay that's the direction I have to go and so sauna is a wonderful way to do it but I
01:49:07
know that's not available to everyone so bathtubs just getting hot when you when I look back through your childhood and
01:49:13
your teenage years and I see all this pain you know um there's a lot of I've
01:49:18
had a lot of pain five years old you're in hospital um nurses are forcing you
01:49:24
down as you go through your teenage years you were in a really dark place mentally you as you said you were res
01:49:30
suicidal and you tried to overdose on medicine I think I was a early I was
01:49:36
talking to my husband about this the other day I think I was a really early version of what we're seeing with so many young people today I think I was um
01:49:43
you know I was brought up on a lot of ultra processed foods as ultr processes they would have been in those days a lot of Wonderbread and baloney and you know
01:49:50
Vita cheese I don't know what you have here but you know like a processed cheese blob and I think that my falling
01:49:59
apart of my health and my mental wellbeing in my teenage years was a direct result of just severe malnutrition and Ultra processed food
01:50:07
addiction did you have ADHD as well yeah they called it hyperkinetic and you know what the
01:50:12
solution was they said get her a dog and make sure she's always physically active and keep her away from White Foods so
01:50:19
breads cookies crackers processed foods right that was a process as it got and I
01:50:24
I always think of that old doctor in that advice because it was perfect it it's perfect whenever I have a patient
01:50:30
who's really ailing I'm like do you have a dog it's really important that you have a dog there's so many reasons but
01:50:36
it's it's just simple stuff and I think what we're seeing now is a very extreme version of that and so many young people
01:50:42
are really really really suffering and my daughter was one of them and she's 24 and her friends are all so sick and have
01:50:49
such Health troubles and it's there's no answers there's only just more drugs
01:50:55
their moms are sick their moms all have autoimmune disease I mean it's just devastating to me you know so to me you
01:51:01
say you know you mentioned like it's hard when we're in this soup of toxins but to me it's I'm P that's my push back
01:51:07
that is how I push back against the system I want to infect as many people as I can with the truth of their
01:51:15
responsibility of taking care of themselves the best way that they can and you don't have to do all of it all at once like I said it's a journey so
01:51:21
just pick one thing like start with the walks or start with the milk jugs and
01:51:27
the push-ups or the squatting your cat I don't care whatever it is but start with one thing and then start to build and
01:51:33
just start making these things habits right just routine and habit routine and habit and to me they're just
01:51:39
non-negotiable it's it's just the way it is and that's the only way I I mean I'm batshit crazy if I don't lift weights
01:51:46
and I don't eat well and I think a lot of people are and I think we just medicate them or we dismiss them or we
01:51:52
just sort allow them to sort of descend further into the misery we can live with
01:51:58
neurod Divergence we can live with I mean I do think I have a bit of neurod Divergence as well or whatever they would have called it back then but I I
01:52:05
think that we can live with these things harmoniously and turn them into superpowers so long as we take good care
01:52:11
of ourselves I had a whole career built off of helping people with chronic pain because I understood it because I had
01:52:16
lived with chronic pain my whole life right like I intimately understood how to help them and I thought outside the box because I knew what it felt like and
01:52:23
I just wanted to help them and I I think that that's what it comes down to and you're in your early 30s but when you
01:52:29
get to your late 40s and you start waking up and you're like oh so this is what you know what it feels like
01:52:36
hopefully you'll become more proactive that's when you really start getting into it and then you start seeking out
01:52:41
other options maybe you maybe you will need some bioidentical hormone replacement then you know maybe you'll you'll have a different perspective at
01:52:46
that point a bit as as you go and experience it because we all do right we can be vehemently one way and I'm not
01:52:52
saying are but a lot of people are really dogmatic and I'm like okay well like the people who really hate on OIC
01:52:58
I'm like well it's showing great promise with Alzheimer's and Parkinson's I hope you never need it if you're so
01:53:05
vehemently against it that you won't even consider it you know I don't mean you but just in general like be open-minded and seek knowledge what is
01:53:13
the most important thing that you have to share that maybe we haven't talked about is there anything that we've
01:53:19
missed I would honestly just say always seek knowledge always be learning always be seeking
01:53:25
knowledge always be open-minded to different things even if you've taken a hard stance on something consider
01:53:30
alternatives and when you hear people telling the truth or it sounds like they're telling the truth double check
01:53:35
them look up sources don't just follow influencers don't just follow what
01:53:41
someone says on Instagram or what someone says on a podcast go look it up and learn more I often are PL I'm
01:53:48
planting seeds for my audience often and I will tell them something and they want all the information right then and I'm like no no no I'm trying to get you to
01:53:55
actually go look up more information I want everyone in my audience to be a knowledge Seeker because that is how you
01:54:01
learn and that is how you grow and that's how you stay on top of it and that's how you stay one step ahead right
01:54:06
I have a closing tradition on this podcast as well where the last guest leaves a question for the next guest not
01:54:12
knowing who they're going to be leaving it for and the question left in the D hero for you is
01:54:19
see when you reach the end of your life what has brought you the most joy and is
01:54:24
that the thing you're most proud of yes I have picked a hard path for
01:54:31
myself I I I always try to be brave and tell the
01:54:36
truth as I know it and it's not always popular and as my audience grows it gets harder because I get more and more push
01:54:42
back but I refuse to step down when I find something that can help people I have dedicated my life to trying to get
01:54:50
that message out to as many people as I can if it would be helpful to them and so while it at times I've
01:54:57
felt like what have I done why why why do I keep doing I feel like Jonah bark at times you know I'm I'm the girl over
01:55:03
here with the early unpopular opinion but I feel proud of that I know my daughter is proud of me and I know that
01:55:09
I've helped a lot of people a lot I know a lot of people have and they've come back to me and said you saved my life in
01:55:15
one way or another and I'm really proud of that and that's I just want to be of service as best I can and my gift I I
01:55:22
think is uh taking complicated information and explaining it simplistically so that people can
01:55:27
Implement and while that's been hard and challenging and I've received a ton of push back that has aged me and made me
01:55:34
sick at times I'm really proud of that Dr Tina Mo I find it so interesting you
01:55:40
know because um it's an idea this idea of micro doing as MC is not one that I've come across
01:55:45
before I discovered your work online and I'm of the contingent where I like to
01:55:51
hear new ideas that maybe haven't had all the clinical studies run on them
01:55:57
before but I like to I like to imagine the possibilities
01:56:03
and then obviously there are scientists that are going to do the research and that that research is going to continue for many decades to come but I'm I'm
01:56:10
intrigued by it I'm curious by it it doesn't mean that I'm going to go on Google and start micro doing myself in my bedroom I'm absolutely not going to
01:56:16
do but I like I like how it assembles a picture in my mind about this new thing
01:56:21
and the poal possibilities of this new thing so that's why I wanted to have the conversation today and I think as you've
01:56:28
clearly said everybody listening should do their own research they should go out there they should speak to their doctor
01:56:34
they should look at the studies that we've cited today they should do their own independent research to form their own view but I think all progress starts
01:56:41
with these sort of initial hypothesis these sort of anecdotal experiences and then Society eventually catches up or
01:56:49
Society proves that that hypothesis was something else or wrong in some way and that's why I have these conversations
01:56:55
because I think it's you know when I think handled in the right way and when presented with the Nuance of all these
01:57:00
subjects they can be the start of a snowball that can cause Society to start
01:57:06
asking questions and through that debate and through that investigation we can hopefully arrive at a better place and I
01:57:12
especially like these conversations when I believe that someone's intent and their intentions are so pure and so well-intentioned and that's certainly
01:57:18
the case for you so thank you so much for the work you're doing all the wonderful people you've helped I've seen so many hundreds of comments from people
01:57:25
that have um benefited from the work that you do and I think that's a remarkable thing and a Force for good in
01:57:31
the world so it's been a pleasure to speak to you today and thank you for making the journey despite the honeyed disc thank you so much for having me
01:57:37
it's a true honor [Music]
01:57:52
a
01:57:59
[Music]

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Episode Highlights

  • Transformative Healing
    Tiny doses of treatment can lead to life-changing health improvements.
    “With tiny doses of this, it's like opening a window of opportunity.”
    @ 00m 05s
    July 04, 2024
  • A Personal Journey
    Dr. Tina shares her emotional experience of saving her mother's life from Crohn's disease.
    “You saved my life.”
    @ 13m 21s
    July 04, 2024
  • Desperation and Pain
    In 2021, chronic pain left her flat on her back, leading to dark thoughts.
    “If this doesn't get better, I think I'm going to kill myself.”
    @ 23m 42s
    July 04, 2024
  • Healing Through Peptides
    She believes peptides are not just treatments but healing agents for chronic conditions.
    “These peptides are healing, they are anti-inflammatory.”
    @ 40m 13s
    July 04, 2024
  • Cardiovascular Benefits of GLP-1 Agonists
    Recent studies show significant cardiovascular improvements independent of weight loss.
    “Those benefits were independent of weight loss.”
    @ 44m 42s
    July 04, 2024
  • The Fertility Crisis
    Metabolic dysfunction is a major driver of infertility, affecting both men and women.
    “We're looking at a population crisis by 2100.”
    @ 59m 33s
    July 04, 2024
  • The Toxic Soup of Modern Life
    We're swimming in a toxic soup of adulterated food and environmental factors.
    “We are swimming in a toxic soup.”
    @ 01h 04m 18s
    July 04, 2024
  • Genetics vs. Environment
    Genetics may predispose us to health issues, but lifestyle choices can mitigate them.
    “Genetics loads the gun and environment pulls the trigger.”
    @ 01h 09m 21s
    July 04, 2024
  • The Psychology of Hunger
    Hunger is a complex psychological phenomenon tied to dopamine and reward systems.
    “Hunger is much more than a desire for food.”
    @ 01h 25m 43s
    July 04, 2024
  • Risk and Reward in Medicine
    Understanding the risk-reward ratio is crucial in medical decisions and treatments.
    “There's no such thing as a free lunch in life.”
    @ 01h 32m 52s
    July 04, 2024
  • Importance of Sleep Hygiene
    Prioritizing and protecting your sleep is essential for overall health. 'Get the TV out of the room; the bedroom is for sex and sleep.'
    “Get the TV out of the room; the bedroom is for sex and sleep.”
    @ 01h 44m 28s
    July 04, 2024
  • Journey of Health
    Health is a journey, not a destination. Start small and build habits. 'Just pick one thing and start to build.'
    “Just pick one thing and start to build.”
    @ 01h 51m 21s
    July 04, 2024

Episode Quotes

Key Moments

  • Chronic Pain00:57
  • Emotional Reflection16:22
  • Desperation23:42
  • Cardiovascular Health44:42
  • Food Choices1:27:45
  • Strength Training Wins1:43:00
  • Mindset Matters1:46:03
  • Seek Knowledge1:53:19

Words per Minute Over Time

Vibes Breakdown

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