E65: VC markup dynamics, Russia/US tensions over Ukraine, Altos Labs raises $3B, Stripe mafia & more
- Jan 28, 2022
- 1:14:12
- Full Episode
0:00 Chamath's preferred cosplay 1:35 Reflecting on prior investment decisions and markup dynamics 15:20 Rising tensions between US and Russia over Ukraine, Putin's demands, NATO negotiations as the underreported key piece, Obama's savvy Russia dealings 39:16 Bill Ackman buys the Netflix dip, Tesla and Microsoft crush earnings, the Fed signals rate hikes 55:18 Altos Labs raises $3B in the largest Seed round ever, incredible Yamanaka factors breakthrough, dynamics of a richly capitalized bio-moonshot 1:04:08 The Stripe Mafia, Bolt CEO punches up, reflecting on old emails
Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg
Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast
Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg
Intro Video Credit: https://twitter.com/TheZachEffect
Referenced in the show: https://www.bloomberg.com/opinion/articles/2013-05-30/bitcoin-the-perfect-schmuck-insurance https://twitter.com/DavidSacks/status/1480716684038049796 https://medium.com/@jason/do-the-work-skip-the-party-8f2864560195#724a--share-10-78 https://www.nytimes.com/2022/01/16/world/europe/russia-ukraine-invasion.html https://www.defense.gov/News/Transcripts/Transcript/Article/2910061/pentagon-press-secretary-john-kirby-holds-a-press-briefing https://www.theatlantic.com/magazine/archive/2016/04/the-obama-doctrine/471525 https://www.history.com/news/nato-article-5-meaning-history-world-war-2 https://www.latimes.com/opinion/op-ed/la-oe-shifrinson-russia-us-nato-deal--20160530-snap-story.html https://www.worldometers.info/gdp/gdp-by-country https://www.atlanticcouncil.org/blogs/natosource/obama-does-not-believe-invading-ukraine-or-saving-assad-makes-putin-a-player https://www.euractiv.com/section/global-europe/news/germany-agrees-to-axe-nord-stream-2-if-russia-invades-ukraine https://www.wsj.com/articles/william-ackman-takes-stake-in-netflix-11643236690 https://tesla-cdn.thron.com/static/WIIG2L_TSLA_Q4_2021_Update_O7MYNE.pdf?xseo=&response-content-disposition=inline%3Bfilename%3D%22tsla-q4-and-fy-2021-update.pdf%22 https://www.microsoft.com/en-us/Investor/earnings/FY-2022-Q2/press-release-webcast https://www.cnbc.com/2022/01/26/fed-decision-january-2022-.html https://www.tcv.com/tcv-insights/netflix-case-study https://www.cnbc.com/2021/11/16/peloton-files-to-sell-1-billion-in-stock-offering-shares-drop.html https://www.drugdiscoverytrends.com/biotech-altos-labs-emerges-with-3b-in-funding-to-focus-on-cellular-rejuvenation-programming https://www.biorxiv.org/content/10.1101/2022.01.20.477063v1.full.pdf https://twitter.com/theryanking/status/1485784823641755648 https://twitter.com/shaunmmaguire/status/1486082835974811650 https://twitter.com/Jason/status/1486113945790214146 https://twitter.com/shaunmmaguire/status/1486114773209006080 https://twitter.com/Jason/status/1486121975311339520 https://my.pitchbook.com/profile/107633-08/company/profile#deal-history/102358-00T
Brief Summary
The hosts discuss market downturns, venture capital strategies, Ukraine-Russia tensions, and a major investment in life extension technology.
Key points
- Market Insights. Investors discuss the emotional turmoil of market fluctuations and the importance of distinguishing between investments and trades.
- Geopolitical Tensions. The podcast delves into the complexities of the Ukraine-Russia situation and potential U.S. involvement.
- Germany's Energy Dilemma. Germany's reliance on Russian energy complicates its geopolitical stance.
- Putin's Rationality. Putin's actions are often portrayed as aggressive, but they may be rational responses.
- Shifting Foreign Policy Focus. A call to prioritize domestic issues over foreign conflicts.
- Human Cost of Conflict. The potential war in Ukraine could result in significant human suffering.
Episode highlights
- Market InsightsInvestors discuss the emotional turmoil of market fluctuations and the importance of distinguishing between investments and trades.“If I confuse an investment with a trade, I'm done for.”2:49Jan 28, 2022
- Geopolitical TensionsThe podcast delves into the complexities of the Ukraine-Russia situation and potential U.S. involvement.“This is a key part of a very long-term strategy to keep Russia contained.”20:12Jan 28, 2022
- Germany's Energy DilemmaGermany's reliance on Russian energy complicates its geopolitical stance.“Germany relies on Russian energy, and it's a difficult situation.”22:15Jan 28, 2022
- Putin's RationalityPutin's actions are often portrayed as aggressive, but they may be rational responses.“Putin is not crazy; he's responding rationally to threats.”28:33Jan 28, 2022
- Shifting Foreign Policy FocusA call to prioritize domestic issues over foreign conflicts.“We need to focus on issues that matter more deeply to us.”29:17Jan 28, 2022
- Human Cost of ConflictThe potential war in Ukraine could result in significant human suffering.“The cost of war in Ukraine will lead to more human suffering.”31:56Jan 28, 2022
- Risk of RecessionExperts warn that the risk of recession is significantly higher now than before.“The risk of recession now is much higher than it was even a month ago.”43:42Jan 28, 2022
- Supply Chain IssuesThe economy faces serious risks from ongoing supply chain disruptions affecting various industries.“The real risk to the economy right now is when and how we're going to work our way through the supply chain issues.”51:40Jan 28, 2022





